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Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: Implications for mechanisms of immune evasion and design of vaccine immunogens.
Chen W, Streaker ED, Russ DE, Feng Y, Prabakaran P, Dimitrov DS. Chen W, et al. Biochem Biophys Res Commun. 2012 Jan 27;417(4):1164-9. doi: 10.1016/j.bbrc.2011.12.089. Epub 2011 Dec 27. Biochem Biophys Res Commun. 2012. PMID: 22226962 Free PMC article.
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens.
Xiao X, Chen W, Feng Y, Zhu Z, Prabakaran P, Wang Y, Zhang MY, Longo NS, Dimitrov DS. Xiao X, et al. Among authors: chen w. Biochem Biophys Res Commun. 2009 Dec 18;390(3):404-9. doi: 10.1016/j.bbrc.2009.09.029. Epub 2009 Sep 11. Biochem Biophys Res Commun. 2009. PMID: 19748484 Free PMC article.
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies.
Zhu Z, Qin HR, Chen W, Zhao Q, Shen X, Schutte R, Wang Y, Ofek G, Streaker E, Prabakaran P, Fouda GG, Liao HX, Owens J, Louder M, Yang Y, Klaric KA, Moody MA, Mascola JR, Scott JK, Kwong PD, Montefiori D, Haynes BF, Tomaras GD, Dimitrov DS. Zhu Z, et al. Among authors: chen w. J Virol. 2011 Nov;85(21):11401-8. doi: 10.1128/JVI.05312-11. Epub 2011 Aug 31. J Virol. 2011. PMID: 21880764 Free PMC article.
Candidate antibody-based therapeutics against HIV-1.
Gong R, Chen W, Dimitrov DS. Gong R, et al. Among authors: chen w. BioDrugs. 2012 Jun 1;26(3):143-62. doi: 10.2165/11631400-000000000-00000. BioDrugs. 2012. PMID: 22462520 Free PMC article. Review.
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