Hegazy GH - Search Results

1

Design, synthesis, biological evaluation, and comparative Cox1 and Cox2 docking of p-substituted benzylidenamino phenyl esters of ibuprofenic and mefenamic acids.

Hegazy GH, Ali HI. Hegazy GH, et al. Bioorg Med Chem. 2012 Feb 1;20(3):1259-70. doi: 10.1016/j.bmc.2011.12.030. Epub 2011 Dec 22. Bioorg Med Chem. 2012. PMID: 22225915

2

Synthesis, docking and biological activities of novel hybrids celecoxib and anthraquinone analogs as potent cytotoxic agents.

Almutairi MS, Hegazy GH, Haiba ME, Ali HI, Khalifa NM, Soliman Ael-M. Almutairi MS, et al. Among authors: hegazy gh. Int J Mol Sci. 2014 Dec 5;15(12):22580-603. doi: 10.3390/ijms151222580. Int J Mol Sci. 2014. PMID: 25490139 Free PMC article.

3

Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents.

Abadi AH, Hegazy GH, El-Zaher AA. Abadi AH, et al. Among authors: hegazy gh. Bioorg Med Chem. 2005 Oct 15;13(20):5759-65. doi: 10.1016/j.bmc.2005.05.053. Bioorg Med Chem. 2005. PMID: 16002298

4

Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors.

Al-Ashmawy AAK, Ragab FA, Elokely KM, Anwar MM, Perez-Leal O, Rico MC, Gordon J, Bichenkov E, Mateo G, Kassem EMM, Hegazy GH, Abou-Gharbia M, Childers W. Al-Ashmawy AAK, et al. Among authors: hegazy gh. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3117-3122. doi: 10.1016/j.bmcl.2017.05.044. Epub 2017 May 15. Bioorg Med Chem Lett. 2017. PMID: 28571824

5

New ibuprofen derivatives as H₂S and NO donors as safer anti-inflammatory agents.

Hassan GS, Hegazy GH, Ibrahim NM, Fahim SH. Hassan GS, et al. Among authors: hegazy gh. Future Med Chem. 2019 Dec;11(23):3029-3045. doi: 10.4155/fmc-2018-0467. Epub 2019 Nov 4. Future Med Chem. 2019. PMID: 31680552

6

Synthesis, anticonvulsant activity and molecular modeling study of some new hydrazinecarbothioamide, benzenesulfonohydrazide, and phenacylacetohydrazide analogues of 4(3H)-quinazolinone.

Al-Salem HS, Hegazy GH, El-Taher KE, El-Messery SM, Al-Obaid AM, El-Subbagh HI. Al-Salem HS, et al. Among authors: hegazy gh. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1490-9. doi: 10.1016/j.bmcl.2015.02.025. Epub 2015 Feb 20. Bioorg Med Chem Lett. 2015. PMID: 25754489

7

Synthesis of some floctafenine derivatives of expected anti-inflammatory/analgesic activity.

Hegazy GH, Taher A, El-Zaher AA. Hegazy GH, et al. Arch Pharm (Weinheim). 2005 Aug;338(8):378-84. doi: 10.1002/ardp.200400959. Arch Pharm (Weinheim). 2005. PMID: 16041835

8

Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents.

Arafa RK, Hegazy GH, Piazza GA, Abadi AH. Arafa RK, et al. Among authors: hegazy gh. Eur J Med Chem. 2013 May;63:826-32. doi: 10.1016/j.ejmech.2013.03.008. Epub 2013 Mar 16. Eur J Med Chem. 2013. PMID: 23584545

9

Design, synthesis, and pharmacological characterization of some 2-substituted-3-phenyl-quinazolin-4(3H)-one derivatives as phosphodiesterase inhibitors.

Amin KM, Hegazy GH, George RF, Ibrahim NR, Mohamed NM. Amin KM, et al. Among authors: hegazy gh. Arch Pharm (Weinheim). 2021 Sep;354(9):e2100051. doi: 10.1002/ardp.202100051. Epub 2021 May 11. Arch Pharm (Weinheim). 2021. PMID: 33977557

10

Design and synthesis of novel benzopyran-2-one derivatives of expected antimicrobial activity through DNA gyrase-B inhibition.

Hassan GS, Farag NA, Hegazy GH, Arafa RK. Hassan GS, et al. Among authors: hegazy gh. Arch Pharm (Weinheim). 2008 Nov;341(11):725-33. doi: 10.1002/ardp.200700266. Arch Pharm (Weinheim). 2008. PMID: 18973170

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