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Emerging cellular targets for influenza antiviral agents.
Müller KH, Kakkola L, Nagaraj AS, Cheltsov AV, Anastasina M, Kainov DE. Müller KH, et al. Among authors: kainov de. Trends Pharmacol Sci. 2012 Feb;33(2):89-99. doi: 10.1016/j.tips.2011.10.004. Epub 2011 Dec 22. Trends Pharmacol Sci. 2012. PMID: 22196854 Review.
Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection.
Denisova OV, Kakkola L, Feng L, Stenman J, Nagaraj A, Lampe J, Yadav B, Aittokallio T, Kaukinen P, Ahola T, Kuivanen S, Vapalahti O, Kantele A, Tynell J, Julkunen I, Kallio-Kokko H, Paavilainen H, Hukkanen V, Elliott RM, De Brabander JK, Saelens X, Kainov DE. Denisova OV, et al. Among authors: de brabander jk, kainov de. J Biol Chem. 2012 Oct 12;287(42):35324-35332. doi: 10.1074/jbc.M112.392142. Epub 2012 Aug 21. J Biol Chem. 2012. PMID: 22910914 Free PMC article.
Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice.
Kakkola L, Denisova OV, Tynell J, Viiliäinen J, Ysenbaert T, Matos RC, Nagaraj A, Ohman T, Kuivanen S, Paavilainen H, Feng L, Yadav B, Julkunen I, Vapalahti O, Hukkanen V, Stenman J, Aittokallio T, Verschuren EW, Ojala PM, Nyman T, Saelens X, Dzeyk K, Kainov DE. Kakkola L, et al. Among authors: kainov de. Cell Death Dis. 2013 Jul 25;4(7):e742. doi: 10.1038/cddis.2013.267. Cell Death Dis. 2013. PMID: 23887633 Free PMC article.
Akt inhibitor MK2206 prevents influenza pH1N1 virus infection in vitro.
Denisova OV, Söderholm S, Virtanen S, Von Schantz C, Bychkov D, Vashchinkina E, Desloovere J, Tynell J, Ikonen N, Theisen LL, Nyman TA, Matikainen S, Kallioniemi O, Julkunen I, Muller CP, Saelens X, Verkhusha VV, Kainov DE. Denisova OV, et al. Among authors: kainov de. Antimicrob Agents Chemother. 2014 Jul;58(7):3689-96. doi: 10.1128/AAC.02798-13. Epub 2014 Apr 21. Antimicrob Agents Chemother. 2014. PMID: 24752266 Free PMC article.
90 results