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A SNP in steroid receptor coactivator-1 disrupts a GSK3β phosphorylation site and is associated with altered tamoxifen response in bone.
Hartmaier RJ, Richter AS, Gillihan RM, Sallit JZ, McGuire SE, Wang J, Lee AV, Osborne CK, O'Malley BW, Brown PH, Xu J, Skaar TC, Philips S, Rae JM, Azzouz F, Li L, Hayden J, Henry NL, Nguyen AT, Stearns V, Hayes DF, Flockhart DA, Oesterreich S. Hartmaier RJ, et al. Among authors: li l. Mol Endocrinol. 2012 Feb;26(2):220-7. doi: 10.1210/me.2011-1032. Epub 2011 Dec 15. Mol Endocrinol. 2012. PMID: 22174377 Free PMC article.
Association between CYP2D6 genotype and tamoxifen-induced hot flashes in a prospective cohort.
Henry NL, Rae JM, Li L, Azzouz F, Skaar TC, Desta Z, Sikora MJ, Philips S, Nguyen AT, Storniolo AM, Hayes DF, Flockhart DA, Stearns V; Consortium on Breast Cancer Pharmacogenomics Investigators. Henry NL, et al. Among authors: li l. Breast Cancer Res Treat. 2009 Oct;117(3):571-5. doi: 10.1007/s10549-009-0309-1. Epub 2009 Jan 20. Breast Cancer Res Treat. 2009. PMID: 19153830 Free PMC article. Clinical Trial.
Genetic associations with toxicity-related discontinuation of aromatase inhibitor therapy for breast cancer.
Henry NL, Skaar TC, Dantzer J, Li L, Kidwell K, Gersch C, Nguyen AT, Rae JM, Desta Z, Oesterreich S, Philips S, Carpenter JS, Storniolo AM, Stearns V, Hayes DF, Flockhart DA. Henry NL, et al. Among authors: li l. Breast Cancer Res Treat. 2013 Apr;138(3):807-16. doi: 10.1007/s10549-013-2504-3. Epub 2013 Apr 2. Breast Cancer Res Treat. 2013. PMID: 23546553 Free PMC article. Clinical Trial.
Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover.
Oesterreich S, Henry NL, Kidwell KM, Van Poznak CH, Skaar TC, Dantzer J, Li L, Hangartner TN, Peacock M, Nguyen AT, Rae JM, Desta Z, Philips S, Storniolo AM, Stearns V, Hayes DF, Flockhart DA. Oesterreich S, et al. Among authors: li l. Breast Cancer Res Treat. 2015 Nov;154(2):263-73. doi: 10.1007/s10549-015-3608-8. Epub 2015 Nov 4. Breast Cancer Res Treat. 2015. PMID: 26536870 Free PMC article.
ESR1 and PGR polymorphisms are associated with estrogen and progesterone receptor expression in breast tumors.
Hertz DL, Henry NL, Kidwell KM, Thomas D, Goddard A, Azzouz F, Speth K, Li L, Banerjee M, Thibert JN, Kleer CG, Stearns V, Hayes DF, Skaar TC, Rae JM. Hertz DL, et al. Among authors: li l. Physiol Genomics. 2016 Sep 1;48(9):688-98. doi: 10.1152/physiolgenomics.00065.2016. Epub 2016 Aug 19. Physiol Genomics. 2016. PMID: 27542969 Free PMC article.
Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results.
Hayes DF, Skaar TC, Rae JM, Henry NL, Nguyen AT, Stearns V, Li L, Philips S, Desta Z, Flockhart DA; Consortium on Breast Cancer Pharmacogenomics (COBRA). Hayes DF, et al. Among authors: li l. Clin Pharmacol Ther. 2010 Nov;88(5):626-9. doi: 10.1038/clpt.2010.143. Epub 2010 Sep 8. Clin Pharmacol Ther. 2010. PMID: 20827267 Free PMC article. Clinical Trial.
Aromatase inhibitor-induced modulation of breast density: clinical and genetic effects.
Henry NL, Chan HP, Dantzer J, Goswami CP, Li L, Skaar TC, Rae JM, Desta Z, Khouri N, Pinsky R, Oesterreich S, Zhou C, Hadjiiski L, Philips S, Robarge J, Nguyen AT, Storniolo AM, Flockhart DA, Hayes DF, Helvie MA, Stearns V. Henry NL, et al. Among authors: li l. Br J Cancer. 2013 Oct 29;109(9):2331-9. doi: 10.1038/bjc.2013.587. Epub 2013 Oct 1. Br J Cancer. 2013. PMID: 24084768 Free PMC article. Clinical Trial.
CYP2D6 genotype and tamoxifen response.
Rae JM, Goetz MP, Hayes DF, Ingle JN, Li L, Storniolo AM, Stearns V, Flockhart DA. Rae JM, et al. Among authors: li l. Breast Cancer Res. 2005 Jul 29;7(5):E6. doi: 10.1186/bcr1297. Breast Cancer Res. 2005. PMID: 16168100 Free PMC article. No abstract available.
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