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Page 1
BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.
Drost R, Bouwman P, Rottenberg S, Boon U, Schut E, Klarenbeek S, Klijn C, van der Heijden I, van der Gulden H, Wientjens E, Pieterse M, Catteau A, Green P, Solomon E, Morris JR, Jonkers J. Drost R, et al. Among authors: rottenberg s. Cancer Cell. 2011 Dec 13;20(6):797-809. doi: 10.1016/j.ccr.2011.11.014. Cancer Cell. 2011. PMID: 22172724 Free article.
Profiling the heterogeneity of colorectal cancer consensus molecular subtypes using spatial transcriptomics.
Valdeolivas A, Amberg B, Giroud N, Richardson M, Gálvez EJC, Badillo S, Julien-Laferrière A, Túrós D, Voith von Voithenberg L, Wells I, Pesti B, Lo AA, Yángüez E, Das Thakur M, Bscheider M, Sultan M, Kumpesa N, Jacobsen B, Bergauer T, Saez-Rodriguez J, Rottenberg S, Schwalie PC, Hahn K. Valdeolivas A, et al. Among authors: rottenberg s. NPJ Precis Oncol. 2024 Jan 10;8(1):10. doi: 10.1038/s41698-023-00488-4. NPJ Precis Oncol. 2024. PMID: 38200223 Free PMC article.
Further evidence for BRCA1 communication with the inactive X chromosome.
Silver DP, Dimitrov SD, Feunteun J, Gelman R, Drapkin R, Lu SD, Shestakova E, Velmurugan S, Denunzio N, Dragomir S, Mar J, Liu X, Rottenberg S, Jonkers J, Ganesan S, Livingston DM. Silver DP, et al. Among authors: rottenberg s. Cell. 2007 Mar 9;128(5):991-1002. doi: 10.1016/j.cell.2007.02.025. Cell. 2007. PMID: 17350581 Free article.
Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer.
Rottenberg S, Nygren AO, Pajic M, van Leeuwen FW, van der Heijden I, van de Wetering K, Liu X, de Visser KE, Gilhuijs KG, van Tellingen O, Schouten JP, Jonkers J, Borst P. Rottenberg S, et al. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12117-22. doi: 10.1073/pnas.0702955104. Epub 2007 Jul 11. Proc Natl Acad Sci U S A. 2007. PMID: 17626183 Free PMC article.
What makes tumors multidrug resistant?
Borst P, Jonkers J, Rottenberg S. Borst P, et al. Among authors: rottenberg s. Cell Cycle. 2007 Nov 15;6(22):2782-7. doi: 10.4161/cc.6.22.4936. Epub 2007 Aug 23. Cell Cycle. 2007. PMID: 17998803 Review.
How do real tumors become resistant to cisplatin?
Borst P, Rottenberg S, Jonkers J. Borst P, et al. Among authors: rottenberg s. Cell Cycle. 2008 May 15;7(10):1353-9. doi: 10.4161/cc.7.10.5930. Epub 2008 Mar 17. Cell Cycle. 2008. PMID: 18418074 Review.
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs.
Rottenberg S, Jaspers JE, Kersbergen A, van der Burg E, Nygren AO, Zander SA, Derksen PW, de Bruin M, Zevenhoven J, Lau A, Boulter R, Cranston A, O'Connor MJ, Martin NM, Borst P, Jonkers J. Rottenberg S, et al. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17079-84. doi: 10.1073/pnas.0806092105. Epub 2008 Oct 29. Proc Natl Acad Sci U S A. 2008. PMID: 18971340 Free PMC article.
115 results