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A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses.
Freigang S, Eschli B, Harris N, Geuking M, Quirin K, Schrempf S, Zellweger R, Weber J, Hengartner H, Zinkernagel RM. Freigang S, et al. Among authors: hengartner h. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13426-31. doi: 10.1073/pnas.0704423104. Epub 2007 Aug 8. Proc Natl Acad Sci U S A. 2007. PMID: 17686978 Free PMC article.
Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.
Martinic MM, van den Broek MF, Rülicke T, Huber C, Odermatt B, Reith W, Horvath E, Zellweger R, Fink K, Recher M, Eschli B, Hengartner H, Zinkernagel RM. Martinic MM, et al. Among authors: hengartner h. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14435-40. doi: 10.1073/pnas.0606707103. Epub 2006 Sep 18. Proc Natl Acad Sci U S A. 2006. PMID: 16983067 Free PMC article.
Deliberate removal of T cell help improves virus-neutralizing antibody production.
Recher M, Lang KS, Hunziker L, Freigang S, Eschli B, Harris NL, Navarini A, Senn BM, Fink K, Lötscher M, Hangartner L, Zellweger R, Hersberger M, Theocharides A, Hengartner H, Zinkernagel RM. Recher M, et al. Among authors: hengartner h. Nat Immunol. 2004 Sep;5(9):934-42. doi: 10.1038/ni1102. Epub 2004 Aug 8. Nat Immunol. 2004. PMID: 15300247
Extralymphatic virus sanctuaries as a consequence of potent T-cell activation.
Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, Fink K, Freigang S, Georgiev P, Hangartner L, Zellweger R, Bergthaler A, Hegazy AN, Eschli B, Theocharides A, Jeker LT, Merkler D, Odermatt B, Hersberger M, Hengartner H, Zinkernagel RM. Recher M, et al. Among authors: hengartner h. Nat Med. 2007 Nov;13(11):1316-23. doi: 10.1038/nm1670. Epub 2007 Nov 4. Nat Med. 2007. PMID: 17982463 Free PMC article.
427 results