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Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
Bailey-Downs LC, Sosnowska D, Toth P, Mitschelen M, Gautam T, Henthorn JC, Ballabh P, Koller A, Farley JA, Sonntag WE, Csiszar A, Ungvari Z. Bailey-Downs LC, et al. Among authors: mitschelen m. J Gerontol A Biol Sci Med Sci. 2012 Jun;67(6):553-64. doi: 10.1093/gerona/glr197. Epub 2011 Nov 10. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22080499 Free PMC article.
Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
Bailey-Downs LC, Mitschelen M, Sosnowska D, Toth P, Pinto JT, Ballabh P, Valcarcel-Ares MN, Farley J, Koller A, Henthorn JC, Bass C, Sonntag WE, Ungvari Z, Csiszar A. Bailey-Downs LC, et al. Among authors: mitschelen m. J Gerontol A Biol Sci Med Sci. 2012 Apr;67(4):313-29. doi: 10.1093/gerona/glr164. Epub 2011 Oct 21. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22021391 Free PMC article.
Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
Tucsek Z, Toth P, Sosnowska D, Gautam T, Mitschelen M, Koller A, Szalai G, Sonntag WE, Ungvari Z, Csiszar A. Tucsek Z, et al. Among authors: mitschelen m. J Gerontol A Biol Sci Med Sci. 2014 Oct;69(10):1212-26. doi: 10.1093/gerona/glt177. Epub 2013 Nov 22. J Gerontol A Biol Sci Med Sci. 2014. PMID: 24269929 Free PMC article.
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
Toth P, Tucsek Z, Tarantini S, Sosnowska D, Gautam T, Mitschelen M, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Toth P, et al. Among authors: mitschelen m. J Cereb Blood Flow Metab. 2014 Dec;34(12):1887-97. doi: 10.1038/jcbfm.2014.156. Epub 2014 Sep 24. J Cereb Blood Flow Metab. 2014. PMID: 25248835 Free PMC article.
Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
Ashpole NM, Warrington JP, Mitschelen MC, Yan H, Sosnowska D, Gautam T, Farley JA, Csiszar A, Ungvari Z, Sonntag WE. Ashpole NM, et al. Among authors: mitschelen mc. Am J Physiol Heart Circ Physiol. 2014 Sep 15;307(6):H858-68. doi: 10.1152/ajpheart.00308.2014. Epub 2014 Jul 18. Am J Physiol Heart Circ Physiol. 2014. PMID: 25038144 Free PMC article.
IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.
Ashpole NM, Herron JC, Mitschelen MC, Farley JA, Logan S, Yan H, Ungvari Z, Hodges EL, Csiszar A, Ikeno Y, Humphrey MB, Sonntag WE. Ashpole NM, et al. Among authors: mitschelen mc. J Bone Miner Res. 2016 Feb;31(2):443-54. doi: 10.1002/jbmr.2689. Epub 2015 Sep 3. J Bone Miner Res. 2016. PMID: 26260312 Free PMC article.
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