Zorn JA - Search Results

1

Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation.

Zorn JA, Wille H, Wolan DW, Wells JA. Zorn JA, et al. J Am Chem Soc. 2011 Dec 14;133(49):19630-3. doi: 10.1021/ja208350u. Epub 2011 Nov 17. J Am Chem Soc. 2011. PMID: 22066605 Free PMC article.

2

Small-molecule activators of a proenzyme.

Wolan DW, Zorn JA, Gray DC, Wells JA. Wolan DW, et al. Among authors: zorn ja. Science. 2009 Nov 6;326(5954):853-8. doi: 10.1126/science.1177585. Science. 2009. PMID: 19892984 Free PMC article.

3

Turning enzymes ON with small molecules.

Zorn JA, Wells JA. Zorn JA, et al. Nat Chem Biol. 2010 Mar;6(3):179-188. doi: 10.1038/nchembio.318. Nat Chem Biol. 2010. PMID: 20154666

4

Fibrils colocalize caspase-3 with procaspase-3 to foster maturation.

Zorn JA, Wolan DW, Agard NJ, Wells JA. Zorn JA, et al. J Biol Chem. 2012 Sep 28;287(40):33781-95. doi: 10.1074/jbc.M112.386128. Epub 2012 Aug 7. J Biol Chem. 2012. PMID: 22872644 Free PMC article.

5

Unraveling the mechanism of cell death induced by chemical fibrils.

Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Julien O, et al. Among authors: zorn ja. Nat Chem Biol. 2014 Nov;10(11):969-76. doi: 10.1038/nchembio.1639. Epub 2014 Sep 28. Nat Chem Biol. 2014. PMID: 25262416 Free PMC article.

6

Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.

Wang Q, Vogan EM, Nocka LM, Rosen CE, Zorn JA, Harrison SC, Kuriyan J. Wang Q, et al. Among authors: zorn ja. Elife. 2015 Feb 20;4:e06074. doi: 10.7554/eLife.06074. Elife. 2015. PMID: 25699547 Free PMC article.

7

Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels.

Bautista DM, Sigal YM, Milstein AD, Garrison JL, Zorn JA, Tsuruda PR, Nicoll RA, Julius D. Bautista DM, et al. Among authors: zorn ja. Nat Neurosci. 2008 Jul;11(7):772-9. doi: 10.1038/nn.2143. Epub 2008 Jun 22. Nat Neurosci. 2008. PMID: 18568022 Free PMC article.

8

Targeted IgMs agonize ocular targets with extended vitreal exposure.

Chen Y, Paluch M, Zorn JA, Rajan S, Leonard B, Estevez A, Brady J, Chiu H, Phung W, Famili A, Yan M, Ciferri C, Matsumoto ML, Lazar GA, Crowell S, Hass P, Agard NJ. Chen Y, et al. Among authors: zorn ja. MAbs. 2020 Jan-Dec;12(1):1818436. doi: 10.1080/19420862.2020.1818436. MAbs. 2020. PMID: 32936727 Free PMC article.

9

Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.

May BC, Zorn JA, Witkop J, Sherrill J, Wallace AC, Legname G, Prusiner SB, Cohen FE. May BC, et al. Among authors: zorn ja. J Med Chem. 2007 Jan 11;50(1):65-73. doi: 10.1021/jm061045z. J Med Chem. 2007. PMID: 17201410

10

Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).

Zorn JA, Wang Q, Fujimura E, Barros T, Kuriyan J. Zorn JA, et al. PLoS One. 2015 Apr 2;10(4):e0121177. doi: 10.1371/journal.pone.0121177. eCollection 2015. PLoS One. 2015. PMID: 25837374 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

38 results

Search Page

Filters