LaFortune TA - Search Results

1

Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells.

Koul D, Fu J, Shen R, LaFortune TA, Wang S, Tiao N, Kim YW, Liu JL, Ramnarian D, Yuan Y, Garcia-Echevrria C, Maira SM, Yung WK. Koul D, et al. Among authors: lafortune ta. Clin Cancer Res. 2012 Jan 1;18(1):184-95. doi: 10.1158/1078-0432.CCR-11-1558. Epub 2011 Nov 7. Clin Cancer Res. 2012. PMID: 22065080 Free PMC article.

2

NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas.

Liu TJ, Koul D, LaFortune T, Tiao N, Shen RJ, Maira SM, Garcia-Echevrria C, Yung WK. Liu TJ, et al. Among authors: lafortune t. Mol Cancer Ther. 2009 Aug;8(8):2204-10. doi: 10.1158/1535-7163.MCT-09-0160. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671762 Free PMC article.

3

Establishment and characterization of clinically relevant models of ependymoma: a true challenge for targeted therapy.

Guan S, Shen R, Lafortune T, Tiao N, Houghton P, Yung WK, Koul D. Guan S, et al. Neuro Oncol. 2011 Jul;13(7):748-58. doi: 10.1093/neuonc/nor037. Epub 2011 Jun 8. Neuro Oncol. 2011. PMID: 21653596 Free PMC article.

4

Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade.

Liu JL, Mao Z, LaFortune TA, Alonso MM, Gallick GE, Fueyo J, Yung WK. Liu JL, et al. Among authors: lafortune ta. Cancer Res. 2007 Nov 15;67(22):11054-63. doi: 10.1158/0008-5472.CAN-07-1263. Cancer Res. 2007. PMID: 18006852

5

Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo.

Liu TJ, LaFortune T, Honda T, Ohmori O, Hatakeyama S, Meyer T, Jackson D, de Groot J, Yung WK. Liu TJ, et al. Among authors: lafortune t. Mol Cancer Ther. 2007 Apr;6(4):1357-67. doi: 10.1158/1535-7163.MCT-06-0476. Mol Cancer Ther. 2007. PMID: 17431114

6

Inhibition of Akt survival pathway by a small-molecule inhibitor in human glioblastoma.

Koul D, Shen R, Bergh S, Sheng X, Shishodia S, Lafortune TA, Lu Y, de Groot JF, Mills GB, Yung WK. Koul D, et al. Among authors: lafortune ta. Mol Cancer Ther. 2006 Mar;5(3):637-44. doi: 10.1158/1535-7163.MCT-05-0453. Mol Cancer Ther. 2006. PMID: 16546978

7

Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer.

Zhang D, LaFortune TA, Krishnamurthy S, Esteva FJ, Cristofanilli M, Liu P, Lucci A, Singh B, Hung MC, Hortobagyi GN, Ueno NT. Zhang D, et al. Among authors: lafortune ta. Clin Cancer Res. 2009 Nov 1;15(21):6639-48. doi: 10.1158/1078-0432.CCR-09-0951. Epub 2009 Oct 13. Clin Cancer Res. 2009. PMID: 19825949 Free PMC article.

8

Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma.

Milano V, Piao Y, LaFortune T, de Groot J. Milano V, et al. Mol Cancer Ther. 2009 Feb;8(2):394-406. doi: 10.1158/1535-7163.MCT-08-0669. Epub 2009 Feb 3. Mol Cancer Ther. 2009. PMID: 19190119

9

Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser¹⁰ p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer.

Zhang D, Tari AM, Akar U, Arun BK, LaFortune TA, Nieves-Alicea R, Hortobagyi GN, Ueno NT. Zhang D, et al. Among authors: lafortune ta. Mol Cancer Ther. 2010 Nov;9(11):3090-9. doi: 10.1158/1535-7163.MCT-10-0362. Epub 2010 Nov 2. Mol Cancer Ther. 2010. PMID: 21045138 Free PMC article.

10

PEA-15 unphosphorylated at both serine 104 and serine 116 inhibits ovarian cancer cell tumorigenicity and progression through blocking β-catenin.

Lee J, Bartholomeusz C, Krishnamurthy S, Liu P, Saso H, Lafortune TA, Hortobagyi GN, Ueno NT. Lee J, et al. Among authors: lafortune ta. Oncogenesis. 2012 Jul 16;1(7):e22. doi: 10.1038/oncsis.2012.22. Oncogenesis. 2012. PMID: 23552738 Free PMC article.

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