Aplin JD - Search Results

1

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.

Sood A, Salih S, Roh D, Lacharme-Lora L, Parry M, Hardiman B, Keehan R, Grummer R, Winterhager E, Gokhale PJ, Andrews PW, Abbott C, Forbes K, Westwood M, Aplin JD, Ingham E, Papageorgiou I, Berry M, Liu J, Dick AD, Garland RJ, Williams N, Singh R, Simon AK, Lewis M, Ham J, Roger L, Baird DM, Crompton LA, Caldwell MA, Swalwell H, Birch-Machin M, Lopez-Castejon G, Randall A, Lin H, Suleiman MS, Evans WH, Newson R, Case CP. Sood A, et al. Among authors: aplin jd. Nat Nanotechnol. 2011 Nov 6;6(12):824-33. doi: 10.1038/nnano.2011.188. Nat Nanotechnol. 2011. PMID: 22056725

2

Methods for siRNA-mediated reduction of mRNA and protein expression in human placental explants, isolated primary cells and cell lines.

Forbes K, Desforges M, Garside R, Aplin JD, Westwood M. Forbes K, et al. Among authors: aplin jd. Placenta. 2009 Feb;30(2):124-9. doi: 10.1016/j.placenta.2008.10.003. Epub 2008 Nov 13. Placenta. 2009. PMID: 19012963 Free PMC article.

3

Dicer-dependent miRNAs provide an endogenous restraint on cytotrophoblast proliferation.

Forbes K, Farrokhnia F, Aplin JD, Westwood M. Forbes K, et al. Among authors: aplin jd. Placenta. 2012 Jul;33(7):581-5. doi: 10.1016/j.placenta.2012.03.006. Epub 2012 Apr 18. Placenta. 2012. PMID: 22516645

4

MicroRNA regulation of mitogenic signaling networks in the human placenta.

Farrokhnia F, Aplin JD, Westwood M, Forbes K. Farrokhnia F, et al. Among authors: aplin jd. J Biol Chem. 2014 Oct 31;289(44):30404-30416. doi: 10.1074/jbc.M114.587295. Epub 2014 Jul 30. J Biol Chem. 2014. PMID: 25077964 Free PMC article.

5

The tyrosine phosphatase SHP-1 negatively regulates cytotrophoblast proliferation in first-trimester human placenta by modulating EGFR activation.

Forbes K, Skinner L, Aplin JD, Westwood M. Forbes K, et al. Among authors: aplin jd. Cell Mol Life Sci. 2012 Dec;69(23):4029-40. doi: 10.1007/s00018-012-1067-5. Epub 2012 Jul 15. Cell Mol Life Sci. 2012. PMID: 22797910 Free PMC article.

6

In vitro placenta barrier model using primary human trophoblasts, underlying connective tissue and vascular endothelium.

Nishiguchi A, Gilmore C, Sood A, Matsusaki M, Collett G, Tannetta D, Sargent IL, McGarvey J, Halemani ND, Hanley J, Day F, Grant S, Murdoch-Davis C, Kemp H, Verkade P, Aplin JD, Akashi M, Case CP. Nishiguchi A, et al. Among authors: aplin jd. Biomaterials. 2019 Feb;192:140-148. doi: 10.1016/j.biomaterials.2018.08.025. Epub 2018 Aug 25. Biomaterials. 2019. PMID: 30448698

7

Insulin-like growth factor I and II regulate the life cycle of trophoblast in the developing human placenta.

Forbes K, Westwood M, Baker PN, Aplin JD. Forbes K, et al. Among authors: aplin jd. Am J Physiol Cell Physiol. 2008 Jun;294(6):C1313-22. doi: 10.1152/ajpcell.00035.2008. Epub 2008 Apr 9. Am J Physiol Cell Physiol. 2008. PMID: 18400990 Free article.

8

IGF signalling and endocytosis in the human villous placenta in early pregnancy as revealed by comparing quantum dot conjugates with a soluble ligand.

Karolczak-Bayatti M , Forbes K , Horn J , Teesalu T , Harris LK , Westwood M , Aplin JD . Karolczak-Bayatti M , et al. Among authors: aplin jd. Nanoscale. 2019 Jun 27;11(25):12285-12295. doi: 10.1039/c8nr10337b. Nanoscale. 2019. PMID: 31211316 Free article.

9

Transforming growth factor-{beta} (TGF{beta}) receptors I/II differentially regulate TGF{beta}1 and IGF-binding protein-3 mitogenic effects in the human placenta.

Forbes K, Souquet B, Garside R, Aplin JD, Westwood M. Forbes K, et al. Among authors: aplin jd. Endocrinology. 2010 Apr;151(4):1723-31. doi: 10.1210/en.2009-0896. Epub 2010 Feb 19. Endocrinology. 2010. PMID: 20172969

10

The protein-tyrosine phosphatase, SRC homology-2 domain containing protein tyrosine phosphatase-2, is a crucial mediator of exogenous insulin-like growth factor signaling to human trophoblast.

Forbes K, West G, Garside R, Aplin JD, Westwood M. Forbes K, et al. Among authors: aplin jd. Endocrinology. 2009 Oct;150(10):4744-54. doi: 10.1210/en.2009-0166. Epub 2009 Jul 9. Endocrinology. 2009. PMID: 19589868

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