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Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.
Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE, Markowitz SD, Camargo FD, Avruch J. Zhou D, et al. Among authors: dawson d. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1312-20. doi: 10.1073/pnas.1110428108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042863 Free PMC article.
15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers.
Yan M, Rerko RM, Platzer P, Dawson D, Willis J, Tong M, Lawrence E, Lutterbaugh J, Lu S, Willson JK, Luo G, Hensold J, Tai HH, Wilson K, Markowitz SD. Yan M, et al. Among authors: dawson d. Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17468-73. doi: 10.1073/pnas.0406142101. Epub 2004 Dec 1. Proc Natl Acad Sci U S A. 2004. PMID: 15574495 Free PMC article.
15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis.
Myung SJ, Rerko RM, Yan M, Platzer P, Guda K, Dotson A, Lawrence E, Dannenberg AJ, Lovgren AK, Luo G, Pretlow TP, Newman RA, Willis J, Dawson D, Markowitz SD. Myung SJ, et al. Among authors: dawson d. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12098-102. doi: 10.1073/pnas.0603235103. Epub 2006 Jul 31. Proc Natl Acad Sci U S A. 2006. PMID: 16880406 Free PMC article.
15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.
Yan M, Myung SJ, Fink SP, Lawrence E, Lutterbaugh J, Yang P, Zhou X, Liu D, Rerko RM, Willis J, Dawson D, Tai HH, Barnholtz-Sloan JS, Newman RA, Bertagnolli MM, Markowitz SD. Yan M, et al. Among authors: dawson d. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9409-13. doi: 10.1073/pnas.0902367106. Epub 2009 May 22. Proc Natl Acad Sci U S A. 2009. PMID: 19470469 Free PMC article. Clinical Trial.
Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T.
Zhao Y, Zhang X, Guda K, Lawrence E, Sun Q, Watanabe T, Iwakura Y, Asano M, Wei L, Yang Z, Zheng W, Dawson D, Willis J, Markowitz SD, Satake M, Wang Z. Zhao Y, et al. Among authors: dawson d. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2592-7. doi: 10.1073/pnas.0914884107. Epub 2010 Jan 21. Proc Natl Acad Sci U S A. 2010. PMID: 20133777 Free PMC article.
Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.
Guda K, Moinova H, He J, Jamison O, Ravi L, Natale L, Lutterbaugh J, Lawrence E, Lewis S, Willson JK, Lowe JB, Wiesner GL, Parmigiani G, Barnholtz-Sloan J, Dawson DW, Velculescu VE, Kinzler KW, Papadopoulos N, Vogelstein B, Willis J, Gerken TA, Markowitz SD. Guda K, et al. Among authors: dawson dw. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12921-5. doi: 10.1073/pnas.0901454106. Epub 2009 Jul 17. Proc Natl Acad Sci U S A. 2009. PMID: 19617566 Free PMC article.
Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers.
Leary RJ, Lin JC, Cummins J, Boca S, Wood LD, Parsons DW, Jones S, Sjöblom T, Park BH, Parsons R, Willis J, Dawson D, Willson JK, Nikolskaya T, Nikolsky Y, Kopelovich L, Papadopoulos N, Pennacchio LA, Wang TL, Markowitz SD, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Leary RJ, et al. Among authors: dawson d. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16224-9. doi: 10.1073/pnas.0808041105. Epub 2008 Oct 13. Proc Natl Acad Sci U S A. 2008. PMID: 18852474 Free PMC article.
Chemopreventive Efficacy of the Cyclooxygenase-2 (Cox-2) Inhibitor, Celecoxib, Is Predicted by Adenoma Expression of Cox-2 and 15-PGDH.
Wang J, Cho NL, Zauber AG, Hsu M, Dawson D, Srivastava A, Mitchell-Richards KA, Markowitz SD, Bertagnolli MM. Wang J, et al. Among authors: dawson d. Cancer Epidemiol Biomarkers Prev. 2018 Jul;27(7):728-736. doi: 10.1158/1055-9965.EPI-17-0573. Epub 2018 May 16. Cancer Epidemiol Biomarkers Prev. 2018. PMID: 29769213 Free PMC article.
2,235 results