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Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity.
Chessman D, Kostenko L, Lethborg T, Purcell AW, Williamson NA, Chen Z, Kjer-Nielsen L, Mifsud NA, Tait BD, Holdsworth R, Almeida CA, Nolan D, Macdonald WA, Archbold JK, Kellerher AD, Marriott D, Mallal S, Bharadwaj M, Rossjohn J, McCluskey J. Chessman D, et al. Among authors: bharadwaj m. Immunity. 2008 Jun;28(6):822-32. doi: 10.1016/j.immuni.2008.04.020. Immunity. 2008. PMID: 18549801 Free article.
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire.
Illing PT, Vivian JP, Dudek NL, Kostenko L, Chen Z, Bharadwaj M, Miles JJ, Kjer-Nielsen L, Gras S, Williamson NA, Burrows SR, Purcell AW, Rossjohn J, McCluskey J. Illing PT, et al. Among authors: bharadwaj m. Nature. 2012 Jun 28;486(7404):554-8. doi: 10.1038/nature11147. Nature. 2012. PMID: 22722860
Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity.
Kostenko L, Kjer-Nielsen L, Nicholson I, Hudson F, Lucas A, Foley B, Chen K, Lynch K, Nguyen J, Wu AH, Tait BD, Holdsworth R, Mallal S, Rossjohn J, Bharadwaj M, McCluskey J. Kostenko L, et al. Among authors: bharadwaj m. Tissue Antigens. 2011 Jul;78(1):11-20. doi: 10.1111/j.1399-0039.2011.01649.x. Epub 2011 Apr 19. Tissue Antigens. 2011. PMID: 21501118
Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion.
Zernich D, Purcell AW, Macdonald WA, Kjer-Nielsen L, Ely LK, Laham N, Crockford T, Mifsud NA, Bharadwaj M, Chang L, Tait BD, Holdsworth R, Brooks AG, Bottomley SP, Beddoe T, Peh CA, Rossjohn J, McCluskey J. Zernich D, et al. Among authors: bharadwaj m. J Exp Med. 2004 Jul 5;200(1):13-24. doi: 10.1084/jem.20031680. Epub 2004 Jun 28. J Exp Med. 2004. PMID: 15226359 Free PMC article.
281 results