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Active Bax and Bak are functional holins.
Genes Dev. 2011 Nov 1;25(21):2278-90. doi: 10.1101/gad.171645.111. Epub 2011 Oct 17.
Genes Dev. 2011.
PMID: 22006182
Free PMC article.
Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process.
George NM, Targy N, Evans JJ, Zhang L, Luo X.
George NM, et al. Among authors: targy n.
J Biol Chem. 2010 Jan 8;285(2):1384-92. doi: 10.1074/jbc.M109.049924. Epub 2009 Oct 30.
J Biol Chem. 2010.
PMID: 19880508
Free PMC article.
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Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage.
Lopez H, Zhang L, George NM, Liu X, Pang X, Evans JJD, Targy NM, Luo X.
Lopez H, et al. Among authors: targy nm.
J Biol Chem. 2010 May 14;285(20):15016-15026. doi: 10.1074/jbc.M109.086231. Epub 2010 Mar 11.
J Biol Chem. 2010.
PMID: 20223826
Free PMC article.
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TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability.
Boerner BP, George NM, Targy NM, Sarvetnick NE.
Boerner BP, et al. Among authors: targy nm.
Endocrinology. 2013 Nov;154(11):4099-112. doi: 10.1210/en.2013-1197. Epub 2013 Aug 22.
Endocrinology. 2013.
PMID: 23970788
Free PMC article.
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