Northoff H - Search Results

1

Boswellic acids from frankincense inhibit lipopolysaccharide functionality through direct molecular interference.

Henkel A, Kather N, Mönch B, Northoff H, Jauch J, Werz O. Henkel A, et al. Among authors: northoff h. Biochem Pharmacol. 2012 Jan 1;83(1):115-21. doi: 10.1016/j.bcp.2011.09.026. Epub 2011 Oct 5. Biochem Pharmacol. 2012. PMID: 22001311

2

Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense.

Siemoneit U, Koeberle A, Rossi A, Dehm F, Verhoff M, Reckel S, Maier TJ, Jauch J, Northoff H, Bernhard F, Doetsch V, Sautebin L, Werz O. Siemoneit U, et al. Among authors: northoff h. Br J Pharmacol. 2011 Jan;162(1):147-62. doi: 10.1111/j.1476-5381.2010.01020.x. Br J Pharmacol. 2011. PMID: 20840544 Free PMC article.

3

On the interference of boswellic acids with 5-lipoxygenase: mechanistic studies in vitro and pharmacological relevance.

Siemoneit U, Pergola C, Jazzar B, Northoff H, Skarke C, Jauch J, Werz O. Siemoneit U, et al. Among authors: northoff h. Eur J Pharmacol. 2009 Mar 15;606(1-3):246-54. doi: 10.1016/j.ejphar.2009.01.044. Epub 2009 Feb 5. Eur J Pharmacol. 2009. PMID: 19374837

4

Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol.

Koeberle A, Northoff H, Werz O. Koeberle A, et al. Among authors: northoff h. Biochem Pharmacol. 2009 May 1;77(9):1513-21. doi: 10.1016/j.bcp.2009.02.005. Epub 2009 Feb 21. Biochem Pharmacol. 2009. PMID: 19426689

5

A novel C(28)-hydroxylated lupeolic acid suppresses the biosynthesis of eicosanoids through inhibition of cytosolic phospholipase A(2).

Verhoff M, Seitz S, Northoff H, Jauch J, Schaible AM, Werz O. Verhoff M, et al. Among authors: northoff h. Biochem Pharmacol. 2012 Sep 1;84(5):681-91. doi: 10.1016/j.bcp.2012.06.016. Epub 2012 Jun 23. Biochem Pharmacol. 2012. PMID: 22732453

6

Defined Structure-Activity Relationships of Boswellic Acids Determine Modulation of Ca2+ Mobilization and Aggregation of Human Platelets by Boswellia serrata Extracts.

Siemoneit U, Tausch L, Poeckel D, Paul M, Northoff H, Koeberle A, Jauch J, Werz O. Siemoneit U, et al. Among authors: northoff h. Planta Med. 2017 Aug;83(12-13):1020-1027. doi: 10.1055/s-0043-107884. Epub 2017 Apr 12. Planta Med. 2017. PMID: 28403501

7

Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E(2) synthase-1.

Koeberle A, Pollastro F, Northoff H, Werz O. Koeberle A, et al. Among authors: northoff h. Br J Pharmacol. 2009 Mar;156(6):952-61. doi: 10.1111/j.1476-5381.2009.00070.x. Br J Pharmacol. 2009. PMID: 19298395 Free PMC article.

8

Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1.

Koeberle A, Siemoneit U, Bühring U, Northoff H, Laufer S, Albrecht W, Werz O. Koeberle A, et al. Among authors: northoff h. J Pharmacol Exp Ther. 2008 Sep;326(3):975-82. doi: 10.1124/jpet.108.139444. Epub 2008 Jun 11. J Pharmacol Exp Ther. 2008. PMID: 18550688

9

MK-886, an inhibitor of the 5-lipoxygenase-activating protein, inhibits cyclooxygenase-1 activity and suppresses platelet aggregation.

Koeberle A, Siemoneit U, Northoff H, Hofmann B, Schneider G, Werz O. Koeberle A, et al. Among authors: northoff h. Eur J Pharmacol. 2009 Apr 17;608(1-3):84-90. doi: 10.1016/j.ejphar.2009.02.023. Epub 2009 Feb 23. Eur J Pharmacol. 2009. PMID: 19239910

10

Green tea epigallocatechin-3-gallate inhibits microsomal prostaglandin E(2) synthase-1.

Koeberle A, Bauer J, Verhoff M, Hoffmann M, Northoff H, Werz O. Koeberle A, et al. Among authors: northoff h. Biochem Biophys Res Commun. 2009 Oct 16;388(2):350-4. doi: 10.1016/j.bbrc.2009.08.005. Epub 2009 Aug 6. Biochem Biophys Res Commun. 2009. PMID: 19665000

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