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Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity.
Cunha C, Di Ianni M, Bozza S, Giovannini G, Zagarella S, Zelante T, D'Angelo C, Pierini A, Pitzurra L, Falzetti F, Carotti A, Perruccio K, Latgé JP, Rodrigues F, Velardi A, Aversa F, Romani L, Carvalho A. Cunha C, et al. Among authors: rodrigues f. Blood. 2010 Dec 9;116(24):5394-402. doi: 10.1182/blood-2010-04-279307. Epub 2010 Aug 31. Blood. 2010. PMID: 20807886 Free article.
The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferation.
Carvalho A, Osório NS, Saraiva M, Cunha C, Almeida AJ, Teixeira-Coelho M, Ludovico P, Pedrosa J, Pitzurra L, Aversa F, Romani L, Castro AG, Rodrigues F. Carvalho A, et al. Among authors: rodrigues f. PLoS One. 2011;6(11):e28256. doi: 10.1371/journal.pone.0028256. Epub 2011 Nov 23. PLoS One. 2011. PMID: 22132241 Free PMC article.
TLR9 activation dampens the early inflammatory response to Paracoccidioides brasiliensis, impacting host survival.
Menino JF, Saraiva M, Gomes-Alves AG, Lobo-Silva D, Sturme M, Gomes-Rezende J, Saraiva AL, Goldman GH, Cunha C, Carvalho A, Romani L, Pedrosa J, Castro AG, Rodrigues F. Menino JF, et al. Among authors: rodrigues f. PLoS Negl Trop Dis. 2013 Jul 25;7(7):e2317. doi: 10.1371/journal.pntd.0002317. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23936560 Free PMC article.
Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation.
Cunha C, Aversa F, Lacerda JF, Busca A, Kurzai O, Grube M, Löffler J, Maertens JA, Bell AS, Inforzato A, Barbati E, Almeida B, Santos e Sousa P, Barbui A, Potenza L, Caira M, Rodrigues F, Salvatori G, Pagano L, Luppi M, Mantovani A, Velardi A, Romani L, Carvalho A. Cunha C, et al. Among authors: rodrigues f. N Engl J Med. 2014 Jan 30;370(5):421-32. doi: 10.1056/NEJMoa1211161. N Engl J Med. 2014. PMID: 24476432 Free article.
PTX3-Based Genetic Testing for Risk of Aspergillosis After Lung Transplant.
Cunha C, Monteiro AA, Oliveira-Coelho A, Kühne J, Rodrigues F, Sasaki SD, Schio SM, Camargo JJ, Mantovani A, Carvalho A, Pasqualotto AC. Cunha C, et al. Among authors: rodrigues f. Clin Infect Dis. 2015 Dec 15;61(12):1893-4. doi: 10.1093/cid/civ679. Epub 2015 Aug 10. Clin Infect Dis. 2015. PMID: 26261201 No abstract available.
1,822 results