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Page 1
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.
Surakka I, Isaacs A, Karssen LC, Laurila PP, Middelberg RP, Tikkanen E, Ried JS, Lamina C, Mangino M, Igl W, Hottenga JJ, Lagou V, van der Harst P, Mateo Leach I, Esko T, Kutalik Z, Wainwright NW, Struchalin MV, Sarin AP, Kangas AJ, Viikari JS, Perola M, Rantanen T, Petersen AK, Soininen P, Johansson A, Soranzo N, Heath AC, Papamarkou T, Prokopenko I, Tönjes A, Kronenberg F, Döring A, Rivadeneira F, Montgomery GW, Whitfield JB, Kähönen M, Lehtimäki T, Freimer NB, Willemsen G, de Geus EJ, Palotie A, Sandhu MS, Waterworth DM, Metspalu A, Stumvoll M, Uitterlinden AG, Jula A, Navis G, Wijmenga C, Wolffenbuttel BH, Taskinen MR, Ala-Korpela M, Kaprio J, Kyvik KO, Boomsma DI, Pedersen NL, Gyllensten U, Wilson JF, Rudan I, Campbell H, Pramstaller PP, Spector TD, Witteman JC, Eriksson JG, Salomaa V, Oostra BA, Raitakari OT, Wichmann HE, Gieger C, Järvelin MR, Martin NG, Hofman A, McCarthy MI, Peltonen L, van Duijn CM, Aulchenko YS, Ripatti S; ENGAGE Consortium. Surakka I, et al. Among authors: tikkanen e. PLoS Genet. 2011 Oct;7(10):e1002333. doi: 10.1371/journal.pgen.1002333. Epub 2011 Oct 20. PLoS Genet. 2011. PMID: 22028671 Free PMC article.
Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci.
Tukiainen T, Kettunen J, Kangas AJ, Lyytikäinen LP, Soininen P, Sarin AP, Tikkanen E, O'Reilly PF, Savolainen MJ, Kaski K, Pouta A, Jula A, Lehtimäki T, Kähönen M, Viikari J, Taskinen MR, Jauhiainen M, Eriksson JG, Raitakari O, Salomaa V, Järvelin MR, Perola M, Palotie A, Ala-Korpela M, Ripatti S. Tukiainen T, et al. Among authors: tikkanen e. Hum Mol Genet. 2012 Mar 15;21(6):1444-55. doi: 10.1093/hmg/ddr581. Epub 2011 Dec 9. Hum Mol Genet. 2012. PMID: 22156771
Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
Kettunen J, Tukiainen T, Sarin AP, Ortega-Alonso A, Tikkanen E, Lyytikäinen LP, Kangas AJ, Soininen P, Würtz P, Silander K, Dick DM, Rose RJ, Savolainen MJ, Viikari J, Kähönen M, Lehtimäki T, Pietiläinen KH, Inouye M, McCarthy MI, Jula A, Eriksson J, Raitakari OT, Salomaa V, Kaprio J, Järvelin MR, Peltonen L, Perola M, Freimer NB, Ala-Korpela M, Palotie A, Ripatti S. Kettunen J, et al. Among authors: tikkanen e. Nat Genet. 2012 Jan 29;44(3):269-76. doi: 10.1038/ng.1073. Nat Genet. 2012. PMID: 22286219 Free PMC article.
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
Kristiansson K, Perola M, Tikkanen E, Kettunen J, Surakka I, Havulinna AS, Stancáková A, Barnes C, Widen E, Kajantie E, Eriksson JG, Viikari J, Kähönen M, Lehtimäki T, Raitakari OT, Hartikainen AL, Ruokonen A, Pouta A, Jula A, Kangas AJ, Soininen P, Ala-Korpela M, Männistö S, Jousilahti P, Bonnycastle LL, Järvelin MR, Kuusisto J, Collins FS, Laakso M, Hurles ME, Palotie A, Peltonen L, Ripatti S, Salomaa V. Kristiansson K, et al. Among authors: tikkanen e. Circ Cardiovasc Genet. 2012 Apr 1;5(2):242-9. doi: 10.1161/CIRCGENETICS.111.961482. Epub 2012 Mar 7. Circ Cardiovasc Genet. 2012. PMID: 22399527 Free PMC article.
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Taal HR, Huikari V, Bradfield JP, Kerkhof M, Groen-Blokhuis MM, Kreiner-Møller E, Marinelli M, Holst C, Leinonen JT, Perry JR, Surakka I, Pietiläinen O, Kettunen J, Anttila V, Kaakinen M, Sovio U, Pouta A, Das S, Lagou V, Power C, Prokopenko I, Evans DM, Kemp JP, St Pourcain B, Ring S, Palotie A, Kajantie E, Osmond C, Lehtimäki T, Viikari JS, Kähönen M, Warrington NM, Lye SJ, Palmer LJ, Tiesler CM, Flexeder C, Montgomery GW, Medland SE, Hofman A, Hakonarson H, Guxens M, Bartels M, Salomaa V; ReproGen Consortium; Murabito JM, Kaprio J, Sørensen TI, Ballester F, Bisgaard H, Boomsma DI, Koppelman GH, Grant SF, Jaddoe VW, Martin NG, Heinrich J, Pennell CE, Raitakari OT, Eriksson JG, Smith GD, Hyppönen E, Järvelin MR, McCarthy MI, Ripatti S, Widén E; Early Growth Genetics (EGG) Consortium. Cousminer DL, et al. Hum Mol Genet. 2013 Jul 1;22(13):2735-47. doi: 10.1093/hmg/ddt104. Epub 2013 Feb 27. Hum Mol Genet. 2013. PMID: 23449627 Free PMC article.
Genetic Risk Scores Predict Recurrence of Acute Coronary Syndrome.
Vaara S, Tikkanen E, Parkkonen O, Lokki ML, Ripatti S, Perola M, Nieminen MS, Sinisalo J. Vaara S, et al. Among authors: tikkanen e. Circ Cardiovasc Genet. 2016 Apr;9(2):172-8. doi: 10.1161/CIRCGENETICS.115.001271. Epub 2016 Mar 15. Circ Cardiovasc Genet. 2016. PMID: 26980882
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.
Ripatti S, Tikkanen E, Orho-Melander M, Havulinna AS, Silander K, Sharma A, Guiducci C, Perola M, Jula A, Sinisalo J, Lokki ML, Nieminen MS, Melander O, Salomaa V, Peltonen L, Kathiresan S. Ripatti S, et al. Among authors: tikkanen e. Lancet. 2010 Oct 23;376(9750):1393-400. doi: 10.1016/S0140-6736(10)61267-6. Lancet. 2010. PMID: 20971364 Free PMC article.
Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study.
Oikonen M, Tikkanen E, Juhola J, Tuovinen T, Seppälä I, Juonala M, Taittonen L, Mikkilä V, Kähönen M, Ripatti S, Viikari J, Lehtimäki T, Havulinna AS, Kee F, Newton-Cheh C, Peltonen L, Schork NJ, Murray SS, Berenson GS, Chen W, Srinivasan SR, Salomaa V, Raitakari OT. Oikonen M, et al. Among authors: tikkanen e. Hypertension. 2011 Dec;58(6):1079-85. doi: 10.1161/HYPERTENSIONAHA.111.179291. Epub 2011 Oct 24. Hypertension. 2011. PMID: 22025373 Free PMC article.
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