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Page 1
Immunological and molecular features of the tumor microenvironment of long-term survivors of ovarian cancer.
Nelson BH, Hamilton PT, Phung MT, Milne K, Harris B, Thornton S, Stevens DL, Kalaria S, Singh K, Laumont CM, Moss E, Alimujiang A, Meagher NS, Bolithon A, Fereday S, Kennedy CJ, Hendley J, Ariyaratne D, Alsop K, Traficante N, Goode EL, Karnezis AN, Shen H, Richardson J, McKinnon Deurloo C, Chase A, Grout B, Doherty JA, Harris HR, Cushing-Haugen KL, Anglesio MS, Heinze K, Huntsman D, Talhouk A, Hanley GE, Alsop J, Jimenez-Linan M, Pharoah PD, Boros J, Brand AH, Harnett PR, Sharma R, Hecht JL, Sasamoto N, Terry KL, Karlan BY, Lester J, Carney ME, Goodman MT, Hernandez BY, Wilkens LR, Behrens S, Turzanski Fortner R, Fasching PA, Bisinotto C, Candido Dos Reis FJ, Ghatage P, Köbel M, Elishaev E, Modugno F, Cook LS, Le ND, Gentry-Maharaj A, Menon U, García MJ, Rodriguez-Antona C, Farrington KM, Kelemen LE, Kommoss S, Staebler A, Garsed DW, Brenton JD, Piskorz AM, Bowtell DD, DeFazio A, Ramus SJ, Pike MC, Pearce CL. Nelson BH, et al. J Clin Invest. 2024 Oct 29:e179501. doi: 10.1172/JCI179501. Online ahead of print. J Clin Invest. 2024. PMID: 39470729 Free article.
Integrated single cell analysis reveals co-evolution of malignant B cells and tumor micro-environment in transformed follicular lymphoma.
Sarkozy C, Wu S, Takata K, Aoki T, Neriah SB, Milne K, Goodyear T, Strong C, Rastogi T, Hilton LK, Lai D, Sehn LH, Farinha P, Nelson BH, Weng A, Marra M, Scott DW, Craig JW, Steidl C, Roth A. Sarkozy C, et al. Among authors: nelson bh. Cancer Cell. 2024 Sep 9;42(9):1630. doi: 10.1016/j.ccell.2024.07.012. Epub 2024 Aug 15. Cancer Cell. 2024. PMID: 39151424 No abstract available.
Changes in the tumour microenvironment mark the transition from serous borderline tumour to low-grade serous carcinoma.
Vallejos R, Zhantuyakova A, Negri GL, Martin SD, Spencer SE, Thornton S, Leung S, Lynch B, Qin Y, Chow C, Liang B, Zdravko S, Douglas JM, Milne K, Mateyko B, Nelson BH, Howitt BE, Kommoss FK, Horn LC, Hoang L, Singh N, Morin GB, Huntsman DG, Cochrane D. Vallejos R, et al. Among authors: nelson bh. J Pathol. 2024 Oct;264(2):197-211. doi: 10.1002/path.6338. Epub 2024 Jul 31. J Pathol. 2024. PMID: 39081243
Integrated single cell analysis reveals co-evolution of malignant B cells and tumor micro-environment in transformed follicular lymphoma.
Sarkozy C, Wu S, Takata K, Aoki T, Neriah SB, Milne K, Goodyear T, Strong C, Rastogi T, Hilton LK, Lai D, Sehn LH, Farinha P, Nelson BH, Weng A, Marra M, Scott DW, Craig JW, Steidl C, Roth A. Sarkozy C, et al. Among authors: nelson bh. Cancer Cell. 2024 Jun 10;42(6):1003-1017.e6. doi: 10.1016/j.ccell.2024.05.011. Cancer Cell. 2024. PMID: 38861923
N-MYC impairs innate immune signaling in high-grade serous ovarian carcinoma.
Miranda A, Pattnaik S, Hamilton PT, Fuss MA, Kalaria S, Laumont CM, Smazynski J, Mesa M, Banville A, Jiang X, Jenkins R, Cañadas I, Nelson BH. Miranda A, et al. Among authors: nelson bh. Sci Adv. 2024 May 17;10(20):eadj5428. doi: 10.1126/sciadv.adj5428. Epub 2024 May 15. Sci Adv. 2024. PMID: 38748789 Free PMC article.
VOLTA: an enVironment-aware cOntrastive ceLl represenTation leArning for histopathology.
Nakhli R, Rich K, Zhang A, Darbandsari A, Shenasa E, Hadjifaradji A, Thiessen S, Milne K, Jones SJM, McAlpine JN, Nelson BH, Gilks CB, Farahani H, Bashashati A. Nakhli R, et al. Among authors: nelson bh. Nat Commun. 2024 May 10;15(1):3942. doi: 10.1038/s41467-024-48062-1. Nat Commun. 2024. PMID: 38729933 Free PMC article.
Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22.
McComb S, Arbabi-Ghahroudi M, Hay KA, Keller BA, Faulkes S, Rutherford M, Nguyen T, Shepherd A, Wu C, Marcil A, Aubry A, Hussack G, Pinto DM, Ryan S, Raphael S, van Faassen H, Zafer A, Zhu Q, Maclean S, Chattopadhyay A, Gurnani K, Gilbert R, Gadoury C, Iqbal U, Fatehi D, Jezierski A, Huang J, Pon RA, Sigrist M, Holt RA, Nelson BH, Atkins H, Kekre N, Yung E, Webb J, Nielsen JS, Weeratna RD. McComb S, et al. Among authors: nelson bh. Mol Ther Oncol. 2024 Feb 13;32(1):200775. doi: 10.1016/j.omton.2024.200775. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596311 Free PMC article.
Improved overall survival in patients with high-grade serous ovarian cancer is associated with CD16a+ immunologic neighborhoods containing NK cells, T cells and macrophages.
Nersesian S, Arseneau RJ, Mejia JP, Lee SN, Westhaver LP, Griffiths NW, Grantham SR, Meunier L, Communal L, Mukherjee A, Mes-Masson AM, Arnason T, Nelson BH, Boudreau JE. Nersesian S, et al. Among authors: nelson bh. Front Immunol. 2024 Jan 22;14:1307873. doi: 10.3389/fimmu.2023.1307873. eCollection 2023. Front Immunol. 2024. PMID: 38318505 Free PMC article.
A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma.
Brassard J, Hughes MR, Dean P, Hernaez DC, Thornton S, Banville AC, Smazynski J, Warren M, Zhang K, Milne K, Gilks CB, Mes-Masson AM, Huntsman DG, Nelson BH, Roskelley CD, McNagny KM. Brassard J, et al. Among authors: nelson bh. Front Oncol. 2023 Dec 21;13:1286754. doi: 10.3389/fonc.2023.1286754. eCollection 2023. Front Oncol. 2023. PMID: 38188285 Free PMC article.
Spatially Resolved Tumor Microenvironment Predicts Treatment Outcomes in Relapsed/Refractory Hodgkin Lymphoma.
Aoki T, Jiang A, Xu A, Yin Y, Gamboa A, Milne K, Takata K, Miyata-Takata T, Chung S, Rai S, Wu S, Warren M, Strong C, Goodyear T, Morris K, Chong LC, Hav M, Colombo AR, Telenius A, Boyle M, Ben-Neriah S, Power M, Gerrie AS, Weng AP, Karsan A, Roth A, Farinha P, Scott DW, Savage KJ, Nelson BH, Merchant A, Steidl C. Aoki T, et al. Among authors: nelson bh. J Clin Oncol. 2024 Mar 20;42(9):1077-1087. doi: 10.1200/JCO.23.01115. Epub 2023 Dec 19. J Clin Oncol. 2024. PMID: 38113419 Free PMC article.
163 results