Loh CT - Search Results

1

DOTA-amide lanthanide tag for reliable generation of pseudocontact shifts in protein NMR spectra.

Graham B, Loh CT, Swarbrick JD, Ung P, Shin J, Yagi H, Jia X, Chhabra S, Barlow N, Pintacuda G, Huber T, Otting G. Graham B, et al. Among authors: loh ct. Bioconjug Chem. 2011 Oct 19;22(10):2118-25. doi: 10.1021/bc200353c. Epub 2011 Sep 20. Bioconjug Chem. 2011. PMID: 21877751

2

Suppression of isotope scrambling in cell-free protein synthesis by broadband inhibition of PLP enymes for selective 15N-labelling and production of perdeuterated proteins in H2O.

Su XC, Loh CT, Qi R, Otting G. Su XC, et al. Among authors: loh ct. J Biomol NMR. 2011 May;50(1):35-42. doi: 10.1007/s10858-011-9477-5. Epub 2011 Feb 12. J Biomol NMR. 2011. PMID: 21318579

3

High-yield cell-free protein synthesis for site-specific incorporation of unnatural amino acids at two sites.

Ozawa K, Loscha KV, Kuppan KV, Loh CT, Dixon NE, Otting G. Ozawa K, et al. Among authors: loh ct. Biochem Biophys Res Commun. 2012 Feb 24;418(4):652-6. doi: 10.1016/j.bbrc.2012.01.069. Epub 2012 Jan 24. Biochem Biophys Res Commun. 2012. PMID: 22293204

4

Lanthanide tags for site-specific ligation to an unnatural amino acid and generation of pseudocontact shifts in proteins.

Loh CT, Ozawa K, Tuck KL, Barlow N, Huber T, Otting G, Graham B. Loh CT, et al. Bioconjug Chem. 2013 Feb 20;24(2):260-8. doi: 10.1021/bc300631z. Epub 2013 Jan 16. Bioconjug Chem. 2013. PMID: 23294422

5

Iron(III) located in the dinuclear metallo-β-lactamase IMP-1 by pseudocontact shifts.

Carruthers TJ, Carr PD, Loh CT, Jackson CJ, Otting G. Carruthers TJ, et al. Among authors: loh ct. Angew Chem Int Ed Engl. 2014 Dec 15;53(51):14269-72. doi: 10.1002/anie.201408693. Epub 2014 Oct 15. Angew Chem Int Ed Engl. 2014. PMID: 25320022

6

Generation of pseudocontact shifts in proteins with lanthanides using small "clickable" nitrilotriacetic acid and iminodiacetic acid tags.

Loh CT, Graham B, Abdelkader EH, Tuck KL, Otting G. Loh CT, et al. Chemistry. 2015 Mar 23;21(13):5084-92. doi: 10.1002/chem.201406274. Epub 2015 Feb 12. Chemistry. 2015. PMID: 25676727

7

Luminescent Alkyne-Bearing Terbium(III) Complexes and Their Application to Bioorthogonal Protein Labeling.

O'Malley WI, Abdelkader EH, Aulsebrook ML, Rubbiani R, Loh CT, Grace MR, Spiccia L, Gasser G, Otting G, Tuck KL, Graham B. O'Malley WI, et al. Among authors: loh ct. Inorg Chem. 2016 Feb 15;55(4):1674-82. doi: 10.1021/acs.inorgchem.5b02605. Epub 2016 Jan 28. Inorg Chem. 2016. PMID: 26821062

8

Using Paramagnetism to Slow Down Nuclear Relaxation in Protein NMR.

Orton HW, Kuprov I, Loh CT, Otting G. Orton HW, et al. Among authors: loh ct. J Phys Chem Lett. 2016 Dec 1;7(23):4815-4818. doi: 10.1021/acs.jpclett.6b02417. Epub 2016 Nov 14. J Phys Chem Lett. 2016. PMID: 27934036

9

Structure restraints from heteronuclear pseudocontact shifts generated by lanthanide tags at two different sites.

Pearce BJG, Jabar S, Loh CT, Szabo M, Graham B, Otting G. Pearce BJG, et al. Among authors: loh ct. J Biomol NMR. 2017 May;68(1):19-32. doi: 10.1007/s10858-017-0111-z. Epub 2017 Apr 22. J Biomol NMR. 2017. PMID: 28434103

10

Genetically encoded amino acids with tert-butyl and trimethylsilyl groups for site-selective studies of proteins by NMR spectroscopy.

Loh CT, Adams LA, Graham B, Otting G. Loh CT, et al. J Biomol NMR. 2018 Aug;71(4):287-293. doi: 10.1007/s10858-017-0157-y. Epub 2017 Dec 2. J Biomol NMR. 2018. PMID: 29197976

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