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Genome-wide association studies establish that human intelligence is highly heritable and polygenic.
Davies G, Tenesa A, Payton A, Yang J, Harris SE, Liewald D, Ke X, Le Hellard S, Christoforou A, Luciano M, McGhee K, Lopez L, Gow AJ, Corley J, Redmond P, Fox HC, Haggarty P, Whalley LJ, McNeill G, Goddard ME, Espeseth T, Lundervold AJ, Reinvang I, Pickles A, Steen VM, Ollier W, Porteous DJ, Horan M, Starr JM, Pendleton N, Visscher PM, Deary IJ. Davies G, et al. Among authors: visscher pm. Mol Psychiatry. 2011 Oct;16(10):996-1005. doi: 10.1038/mp.2011.85. Epub 2011 Aug 9. Mol Psychiatry. 2011. PMID: 21826061 Free PMC article.
A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.
Davies G, Harris SE, Reynolds CA, Payton A, Knight HM, Liewald DC, Lopez LM, Luciano M, Gow AJ, Corley J, Henderson R, Murray C, Pattie A, Fox HC, Redmond P, Lutz MW, Chiba-Falek O, Linnertz C, Saith S, Haggarty P, McNeill G, Ke X, Ollier W, Horan M, Roses AD, Ponting CP, Porteous DJ, Tenesa A, Pickles A, Starr JM, Whalley LJ, Pedersen NL, Pendleton N, Visscher PM, Deary IJ. Davies G, et al. Among authors: visscher pm. Mol Psychiatry. 2014 Jan;19(1):76-87. doi: 10.1038/mp.2012.159. Epub 2012 Dec 4. Mol Psychiatry. 2014. PMID: 23207651 Free PMC article.
Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.
Benyamin B, Pourcain B, Davis OS, Davies G, Hansell NK, Brion MJ, Kirkpatrick RM, Cents RA, Franić S, Miller MB, Haworth CM, Meaburn E, Price TS, Evans DM, Timpson N, Kemp J, Ring S, McArdle W, Medland SE, Yang J, Harris SE, Liewald DC, Scheet P, Xiao X, Hudziak JJ, de Geus EJ; Wellcome Trust Case Control Consortium 2 (WTCCC2); Jaddoe VW, Starr JM, Verhulst FC, Pennell C, Tiemeier H, Iacono WG, Palmer LJ, Montgomery GW, Martin NG, Boomsma DI, Posthuma D, McGue M, Wright MJ, Davey Smith G, Deary IJ, Plomin R, Visscher PM. Benyamin B, et al. Among authors: visscher pm. Mol Psychiatry. 2014 Feb;19(2):253-8. doi: 10.1038/mp.2012.184. Epub 2013 Jan 29. Mol Psychiatry. 2014. PMID: 23358156 Free PMC article.
Genome-wide autozygosity is associated with lower general cognitive ability.
Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EE, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou A, Steen VM, Hellard SL, Sundet K, Reinvang I, Espeseth T, Lundervold AJ, Giegling I, Konte B, Hartmann AM, Rujescu D, Roussos P, Giakoumaki S, Burdick KE, Bitsios P, Donohoe G, Corley RP, Visscher PM, Pendleton N, Malhotra AK, Neale BM, Lencz T, Keller MC. Howrigan DP, et al. Among authors: visscher pm. Mol Psychiatry. 2016 Jun;21(6):837-43. doi: 10.1038/mp.2015.120. Epub 2015 Sep 22. Mol Psychiatry. 2016. PMID: 26390830 Free PMC article.
Assessing the genetic overlap between BMI and cognitive function.
Marioni RE, Yang J, Dykiert D, Mõttus R, Campbell A; CHARGE Cognitive Working Group; Davies G, Hayward C, Porteous DJ, Visscher PM, Deary IJ. Marioni RE, et al. Among authors: visscher pm. Mol Psychiatry. 2016 Oct;21(10):1477-82. doi: 10.1038/mp.2015.205. Epub 2016 Feb 9. Mol Psychiatry. 2016. PMID: 26857597 Free PMC article.
Variation in the dysbindin gene and normal cognitive function in three independent population samples.
Luciano M, Miyajima F, Lind PA, Bates TC, Horan M, Harris SE, Wright MJ, Ollier WE, Hayward C, Pendleton N, Gow AJ, Visscher PM, Starr JM, Deary IJ, Martin NG, Payton A. Luciano M, et al. Among authors: visscher pm. Genes Brain Behav. 2009 Mar;8(2):218-27. doi: 10.1111/j.1601-183X.2008.00462.x. Epub 2008 Dec 3. Genes Brain Behav. 2009. PMID: 19077176 Free article.
Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion.
Vinkhuyzen AA, Pedersen NL, Yang J, Lee SH, Magnusson PK, Iacono WG, McGue M, Madden PA, Heath AC, Luciano M, Payton A, Horan M, Ollier W, Pendleton N, Deary IJ, Montgomery GW, Martin NG, Visscher PM, Wray NR. Vinkhuyzen AA, et al. Among authors: visscher pm. Transl Psychiatry. 2012 Apr 17;2(4):e102. doi: 10.1038/tp.2012.27. Transl Psychiatry. 2012. PMID: 22832902 Free PMC article.
590 results