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EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms.
Schrøder JM, Larsen J, Komarova Y, Akhmanova A, Thorsteinsson RI, Grigoriev I, Manguso R, Christensen ST, Pedersen SF, Geimer S, Pedersen LB. Schrøder JM, et al. Among authors: manguso r. J Cell Sci. 2011 Aug 1;124(Pt 15):2539-51. doi: 10.1242/jcs.085852. J Cell Sci. 2011. PMID: 21768326 Free PMC article.
Primary cilia and aberrant cell signaling in epithelial ovarian cancer.
Egeberg DL, Lethan M, Manguso R, Schneider L, Awan A, Jørgensen TS, Byskov AG, Pedersen LB, Christensen ST. Egeberg DL, et al. Among authors: manguso r. Cilia. 2012 Aug 10;1(1):15. doi: 10.1186/2046-2530-1-15. Cilia. 2012. PMID: 23351307 Free PMC article.
An expanded universe of cancer targets.
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS; Cancer Target Discovery and Development Network. Hahn WC, et al. Cell. 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. Cell. 2021. PMID: 33667368 Free PMC article. Review.
Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer.
Biancur DE, Kapner KS, Yamamoto K, Banh RS, Neggers JE, Sohn ASW, Wu W, Manguso RT, Brown A, Root DE, Aguirre AJ, Kimmelman AC. Biancur DE, et al. Cell Metab. 2021 Jan 5;33(1):199-210.e8. doi: 10.1016/j.cmet.2020.10.018. Epub 2020 Nov 4. Cell Metab. 2021. PMID: 33152323 Free PMC article.
PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment.
Collins NB, Al Abosy R, Miller BC, Bi K, Zhao Q, Quigley M, Ishizuka JJ, Yates KB, Pope HW, Manguso RT, Shrestha Y, Wadsworth M, Hughes T, Shalek AK, Boehm JS, Hahn WC, Doench JG, Haining WN. Collins NB, et al. Among authors: manguso rt. J Immunother Cancer. 2022 Mar;10(3):e003402. doi: 10.1136/jitc-2021-003402. J Immunother Cancer. 2022. PMID: 35264433 Free PMC article.
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.
Manguso RT, Pope HW, Zimmer MD, Brown FD, Yates KB, Miller BC, Collins NB, Bi K, LaFleur MW, Juneja VR, Weiss SA, Lo J, Fisher DE, Miao D, Van Allen E, Root DE, Sharpe AH, Doench JG, Haining WN. Manguso RT, et al. Nature. 2017 Jul 27;547(7664):413-418. doi: 10.1038/nature23270. Epub 2017 Jul 19. Nature. 2017. PMID: 28723893 Free PMC article.
TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response.
Zeng Z, Wong CJ, Yang L, Ouardaoui N, Li D, Zhang W, Gu S, Zhang Y, Liu Y, Wang X, Fu J, Zhou L, Zhang B, Kim S, Yates KB, Brown M, Freeman GJ, Uppaluri R, Manguso R, Liu XS. Zeng Z, et al. Among authors: manguso r. Nucleic Acids Res. 2022 Jan 7;50(D1):D1391-D1397. doi: 10.1093/nar/gkab804. Nucleic Acids Res. 2022. PMID: 34534350 Free PMC article.
Checkpoint blockade-induced CD8+ T cell differentiation in head and neck cancer responders.
Zhou L, Zeng Z, Egloff AM, Zhang F, Guo F, Campbell KM, Du P, Fu J, Zolkind P, Ma X, Zhang Z, Zhang Y, Wang X, Gu S, Riley R, Nakahori Y, Keegan J, Haddad R, Schoenfeld JD, Griffith O, Manguso RT, Lederer JA, Liu XS, Uppaluri R. Zhou L, et al. Among authors: manguso rt. J Immunother Cancer. 2022 Jan;10(1):e004034. doi: 10.1136/jitc-2021-004034. J Immunother Cancer. 2022. PMID: 35058328 Free PMC article.
31 results