Dong G - Search Results

1

Synthesis of 9-(heteroarylmethylidene)amino derivatives of homocamptothecin with biological activities.

Guo W, Miao Z, Sheng C, Yao J, Liu W, Zhu L, Zhang Y, Cheng P, Dong G, Zhuang C, Zhang W. Guo W, et al. Among authors: dong g. Chem Biodivers. 2011 Jul;8(7):1266-73. doi: 10.1002/cbdv.201000271. Chem Biodivers. 2011. PMID: 21766447

2

Homology modeling and molecular dynamics simulation of N-myristoyltransferase from protozoan parasites: active site characterization and insights into rational inhibitor design.

Sheng C, Ji H, Miao Z, Che X, Yao J, Wang W, Dong G, Guo W, Lü J, Zhang W. Sheng C, et al. Among authors: dong g. J Comput Aided Mol Des. 2009 Jun;23(6):375-89. doi: 10.1007/s10822-009-9267-2. Epub 2009 Apr 16. J Comput Aided Mol Des. 2009. PMID: 19370313

3

Three-dimensional model of lanosterol 14 alpha-demethylase from Cryptococcus neoformans: active-site characterization and insights into azole binding.

Sheng C, Miao Z, Ji H, Yao J, Wang W, Che X, Dong G, Lü J, Guo W, Zhang W. Sheng C, et al. Among authors: dong g. Antimicrob Agents Chemother. 2009 Aug;53(8):3487-95. doi: 10.1128/AAC.01630-08. Epub 2009 May 26. Antimicrob Agents Chemother. 2009. PMID: 19470512 Free PMC article.

4

New azoles with potent antifungal activity: design, synthesis and molecular docking.

Che X, Sheng C, Wang W, Cao Y, Xu Y, Ji H, Dong G, Miao Z, Yao J, Zhang W. Che X, et al. Among authors: dong g. Eur J Med Chem. 2009 Oct;44(10):4218-26. doi: 10.1016/j.ejmech.2009.05.018. Epub 2009 May 24. Eur J Med Chem. 2009. PMID: 19539408

5

Evolutionary trace analysis of CYP51 family: implication for site-directed mutagenesis and novel antifungal drug design.

Sheng C, Chen S, Ji H, Dong G, Che X, Wang W, Miao Z, Yao J, Lü J, Guo W, Zhang W. Sheng C, et al. Among authors: dong g. J Mol Model. 2010 Feb;16(2):279-84. doi: 10.1007/s00894-009-0527-9. Epub 2009 Jul 11. J Mol Model. 2010. PMID: 19593597

6

Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization.

Sheng C, Wang W, Che X, Dong G, Wang S, Ji H, Miao Z, Yao J, Zhang W. Sheng C, et al. Among authors: dong g. ChemMedChem. 2010 Mar 1;5(3):390-7. doi: 10.1002/cmdc.200900468. ChemMedChem. 2010. PMID: 20157915

7

Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives.

Xu Y, Sheng C, Wang W, Che X, Cao Y, Dong G, Wang S, Ji H, Miao Z, Yao J, Zhang W. Xu Y, et al. Among authors: dong g. Bioorg Med Chem Lett. 2010 May 1;20(9):2942-5. doi: 10.1016/j.bmcl.2010.03.014. Epub 2010 Mar 7. Bioorg Med Chem Lett. 2010. PMID: 20362444

8

Phosphate ester derivatives of homocamptothecin: synthesis, solution stabilities and antitumor activities.

Miao Z, Zhang J, You L, Wang J, Sheng C, Yao J, Zhang W, Feng H, Guo W, Zhou L, Liu W, Zhu L, Cheng P, Che X, Wang W, Luo C, Xu Y, Dong G. Miao Z, et al. Among authors: dong g. Bioorg Med Chem. 2010 May 1;18(9):3140-6. doi: 10.1016/j.bmc.2010.03.039. Epub 2010 Mar 20. Bioorg Med Chem. 2010. PMID: 20371183

9

Design, synthesis and antifungal activity of isosteric analogues of benzoheterocyclic N-myristoyltransferase inhibitors.

Sheng C, Xu H, Wang W, Cao Y, Dong G, Wang S, Che X, Ji H, Miao Z, Yao J, Zhang W. Sheng C, et al. Among authors: dong g. Eur J Med Chem. 2010 Sep;45(9):3531-40. doi: 10.1016/j.ejmech.2010.03.007. Epub 2010 Mar 12. Eur J Med Chem. 2010. PMID: 20615585

10

Selection of evodiamine as a novel topoisomerase I inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents.

Dong G, Sheng C, Wang S, Miao Z, Yao J, Zhang W. Dong G, et al. J Med Chem. 2010 Nov 11;53(21):7521-31. doi: 10.1021/jm100387d. J Med Chem. 2010. PMID: 20942490

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