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Increased PDE5 activity and decreased Rho kinase and PKC activities in colonic muscle from caveolin-1-/- mice impair the peristaltic reflex and propulsion.
Mahavadi S, Bhattacharya S, Kumar DP, Clay C, Ross G, Akbarali HI, Grider JR, Murthy KS. Mahavadi S, et al. Among authors: kumar dp. Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(12):G964-74. doi: 10.1152/ajpgi.00165.2013. Epub 2013 Oct 24. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 24157969 Free PMC article.
Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway.
Rajagopal S, Kumar DP, Mahavadi S, Bhattacharya S, Zhou R, Corvera CU, Bunnett NW, Grider JR, Murthy KS. Rajagopal S, et al. Among authors: kumar dp. Am J Physiol Gastrointest Liver Physiol. 2013 Mar 1;304(5):G527-35. doi: 10.1152/ajpgi.00388.2012. Epub 2012 Dec 28. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23275618 Free PMC article.
Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG.
Nalli AD, Kumar DP, Al-Shboul O, Mahavadi S, Kuemmerle JF, Grider JR, Murthy KS. Nalli AD, et al. Among authors: kumar dp. Cell Biochem Biophys. 2014 Nov;70(2):867-80. doi: 10.1007/s12013-014-9992-6. Cell Biochem Biophys. 2014. PMID: 24777815 Free PMC article.
Emerging roles of AATF: Checkpoint signaling and beyond.
Srinivas AN, Suresh D, Mirshahi F, Santhekadur PK, Sanyal AJ, Kumar DP. Srinivas AN, et al. Among authors: kumar dp. J Cell Physiol. 2021 May;236(5):3383-3395. doi: 10.1002/jcp.30141. Epub 2020 Nov 4. J Cell Physiol. 2021. PMID: 33145763 Review.
Jun kinase-induced overexpression of leukemia-associated Rho GEF (LARG) mediates sustained hypercontraction of longitudinal smooth muscle in inflammation.
Al-Shboul O, Nalli AD, Kumar DP, Zhou R, Mahavadi S, Kuemmerle JF, Grider JR, Murthy KS. Al-Shboul O, et al. Among authors: kumar dp. Am J Physiol Cell Physiol. 2014 Jun 15;306(12):C1129-41. doi: 10.1152/ajpcell.00021.2014. Epub 2014 Apr 16. Am J Physiol Cell Physiol. 2014. PMID: 24740538 Free PMC article.
87 results