Leverkus M - Search Results

1

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms.

Feoktistova M, Geserick P, Kellert B, Dimitrova DP, Langlais C, Hupe M, Cain K, MacFarlane M, Häcker G, Leverkus M. Feoktistova M, et al. Among authors: leverkus m. Mol Cell. 2011 Aug 5;43(3):449-63. doi: 10.1016/j.molcel.2011.06.011. Epub 2011 Jul 7. Mol Cell. 2011. PMID: 21737330 Free PMC article.

2

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment.

Geserick P, Hupe M, Moulin M, Wong WW, Feoktistova M, Kellert B, Gollnick H, Silke J, Leverkus M. Geserick P, et al. Among authors: leverkus m. J Cell Biol. 2009 Dec 28;187(7):1037-54. doi: 10.1083/jcb.200904158. J Cell Biol. 2009. PMID: 20038679 Free PMC article.

3

Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex.

Kavuri SM, Geserick P, Berg D, Dimitrova DP, Feoktistova M, Siegmund D, Gollnick H, Neumann M, Wajant H, Leverkus M. Kavuri SM, et al. Among authors: leverkus m. J Biol Chem. 2011 May 13;286(19):16631-46. doi: 10.1074/jbc.M110.148585. Epub 2011 Mar 22. J Biol Chem. 2011. PMID: 21454681 Free PMC article.

4

Pick your poison: the Ripoptosome, a cell death platform regulating apoptosis and necroptosis.

Feoktistova M, Geserick P, Panayotova-Dimitrova D, Leverkus M. Feoktistova M, et al. Among authors: leverkus m. Cell Cycle. 2012 Feb 1;11(3):460-7. doi: 10.4161/cc.11.3.19060. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22274400

5

Characterization of the ripoptosome and its components: implications for anti-inflammatory and cancer therapy.

Schilling R, Geserick P, Leverkus M. Schilling R, et al. Among authors: leverkus m. Methods Enzymol. 2014;545:83-102. doi: 10.1016/B978-0-12-801430-1.00004-4. Methods Enzymol. 2014. PMID: 25065887 Review.

6

Programmed necrosis and necroptosis signalling.

Feoktistova M, Leverkus M. Feoktistova M, et al. Among authors: leverkus m. FEBS J. 2015 Jan;282(1):19-31. doi: 10.1111/febs.13120. Epub 2014 Nov 11. FEBS J. 2015. PMID: 25327580 Free article. Review.

7

Ripoptosome Analysis by Caspase-8 Coimmunoprecipitation.

Feoktistova M, Geserick P, Leverkus M. Feoktistova M, et al. Among authors: leverkus m. Cold Spring Harb Protoc. 2016 Mar 1;2016(3):pdb.prot087403. doi: 10.1101/pdb.prot087403. Cold Spring Harb Protoc. 2016. PMID: 26933246

8

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate.

Hughes MA, Powley IR, Jukes-Jones R, Horn S, Feoktistova M, Fairall L, Schwabe JW, Leverkus M, Cain K, MacFarlane M. Hughes MA, et al. Among authors: leverkus m. Mol Cell. 2016 Mar 17;61(6):834-49. doi: 10.1016/j.molcel.2016.02.023. Mol Cell. 2016. PMID: 26990987 Free PMC article.

9

Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival.

Horn S, Hughes MA, Schilling R, Sticht C, Tenev T, Ploesser M, Meier P, Sprick MR, MacFarlane M, Leverkus M. Horn S, et al. Among authors: leverkus m. Cell Rep. 2017 Apr 25;19(4):785-797. doi: 10.1016/j.celrep.2017.04.010. Cell Rep. 2017. PMID: 28445729 Free PMC article.

10

TNF Is Partially Required for Cell-Death-Triggered Skin Inflammation upon Acute Loss of cFLIP.

Feoktistova M, Makarov R, Leverkus M, Yazdi AS, Panayotova-Dimitrova D. Feoktistova M, et al. Among authors: leverkus m. Int J Mol Sci. 2020 Nov 23;21(22):8859. doi: 10.3390/ijms21228859. Int J Mol Sci. 2020. PMID: 33238518 Free PMC article.

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