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211 results

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Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL. Moran-Crusio K, et al. Among authors: aifantis i. Cancer Cell. 2011 Jul 12;20(1):11-24. doi: 10.1016/j.ccr.2011.06.001. Epub 2011 Jun 30. Cancer Cell. 2011. PMID: 21723200 Free PMC article.
Hedgehog signaling is dispensable for adult hematopoietic stem cell function.
Gao J, Graves S, Koch U, Liu S, Jankovic V, Buonamici S, El Andaloussi A, Nimer SD, Kee BL, Taichman R, Radtke F, Aifantis I. Gao J, et al. Among authors: aifantis i. Cell Stem Cell. 2009 Jun 5;4(6):548-58. doi: 10.1016/j.stem.2009.03.015. Cell Stem Cell. 2009. PMID: 19497283 Free PMC article.
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Buonamici S, Trimarchi T, Ruocco MG, Reavie L, Cathelin S, Mar BG, Klinakis A, Lukyanov Y, Tseng JC, Sen F, Gehrie E, Li M, Newcomb E, Zavadil J, Meruelo D, Lipp M, Ibrahim S, Efstratiadis A, Zagzag D, Bromberg JS, Dustin ML, Aifantis I. Buonamici S, et al. Among authors: aifantis i. Nature. 2009 Jun 18;459(7249):1000-4. doi: 10.1038/nature08020. Nature. 2009. PMID: 19536265 Free PMC article.
The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Espinosa L, Cathelin S, D'Altri T, Trimarchi T, Statnikov A, Guiu J, Rodilla V, Inglés-Esteve J, Nomdedeu J, Bellosillo B, Besses C, Abdel-Wahab O, Kucine N, Sun SC, Song G, Mullighan CC, Levine RL, Rajewsky K, Aifantis I, Bigas A. Espinosa L, et al. Among authors: aifantis i. Cancer Cell. 2010 Sep 14;18(3):268-81. doi: 10.1016/j.ccr.2010.08.006. Cancer Cell. 2010. PMID: 20832754 Free PMC article.
PHF6 mutations in adult acute myeloid leukemia.
Van Vlierberghe P, Patel J, Abdel-Wahab O, Lobry C, Hedvat CV, Balbin M, Nicolas C, Payer AR, Fernandez HF, Tallman MS, Paietta E, Melnick A, Vandenberghe P, Speleman F, Aifantis I, Cools J, Levine R, Ferrando A. Van Vlierberghe P, et al. Among authors: aifantis i. Leukemia. 2011 Jan;25(1):130-4. doi: 10.1038/leu.2010.247. Epub 2010 Oct 29. Leukemia. 2011. PMID: 21030981 Free PMC article.
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.
Klinakis A, Lobry C, Abdel-Wahab O, Oh P, Haeno H, Buonamici S, van De Walle I, Cathelin S, Trimarchi T, Araldi E, Liu C, Ibrahim S, Beran M, Zavadil J, Efstratiadis A, Taghon T, Michor F, Levine RL, Aifantis I. Klinakis A, et al. Among authors: aifantis i. Nature. 2011 May 12;473(7346):230-3. doi: 10.1038/nature09999. Nature. 2011. PMID: 21562564 Free PMC article.
211 results