Meleddu R - Search Results

1

Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey.

Dunkel P, Balogh B, Meleddu R, Maccioni E, Gyires K, Mátyus P. Dunkel P, et al. Among authors: meleddu r. Expert Opin Ther Pat. 2011 Sep;21(9):1453-71. doi: 10.1517/13543776.2011.594040. Epub 2011 Jun 15. Expert Opin Ther Pat. 2011. PMID: 21675926 Review.

2

3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B.

Maccioni E, Alcaro S, Cirilli R, Vigo S, Cardia MC, Sanna ML, Meleddu R, Yanez M, Costa G, Casu L, Matyus P, Distinto S. Maccioni E, et al. Among authors: meleddu r. J Med Chem. 2011 Sep 22;54(18):6394-8. doi: 10.1021/jm2002876. Epub 2011 Aug 17. J Med Chem. 2011. PMID: 21777011

3

Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.

Distinto S, Yáñez M, Alcaro S, Cardia MC, Gaspari M, Sanna ML, Meleddu R, Ortuso F, Kirchmair J, Markt P, Bolasco A, Wolber G, Secci D, Maccioni E. Distinto S, et al. Among authors: meleddu r. Eur J Med Chem. 2012 Feb;48:284-95. doi: 10.1016/j.ejmech.2011.12.027. Epub 2011 Dec 24. Eur J Med Chem. 2012. PMID: 22222137

4

Molecular aspects of the RT/drug interactions. Perspective of dual inhibitors.

Distinto S, Maccioni E, Meleddu R, Corona A, Alcaro S, Tramontano E. Distinto S, et al. Among authors: meleddu r. Curr Pharm Des. 2013;19(10):1850-9. doi: 10.2174/1381612811319100009. Curr Pharm Des. 2013. PMID: 23092286 Review.

5

(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase.

Meleddu R, Distinto S, Corona A, Bianco G, Cannas V, Esposito F, Artese A, Alcaro S, Matyus P, Bogdan D, Cottiglia F, Tramontano E, Maccioni E. Meleddu R, et al. Eur J Med Chem. 2015 Mar 26;93:452-60. doi: 10.1016/j.ejmech.2015.02.032. Epub 2015 Feb 20. Eur J Med Chem. 2015. PMID: 25728026

6

New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII.

Meleddu R, Maccioni E, Distinto S, Bianco G, Melis C, Alcaro S, Cottiglia F, Ceruso M, Supuran CT. Meleddu R, et al. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3281-4. doi: 10.1016/j.bmcl.2015.05.076. Epub 2015 May 30. Bioorg Med Chem Lett. 2015. PMID: 26073006

7

Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida.

Meleddu R, Distinto S, Corona A, Maccioni E, Arridu A, Melis C, Bianco G, Matyus P, Cottiglia F, Sanna A, De Logu A. Meleddu R, et al. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1672-7. doi: 10.3109/14756366.2015.1113171. Epub 2016 Jan 8. J Enzyme Inhib Med Chem. 2016. PMID: 26745285 Free article.

8

Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B.

Meleddu R, Distinto S, Cirilli R, Alcaro S, Yanez M, Sanna ML, Corona A, Melis C, Bianco G, Matyus P, Cottiglia F, Maccioni E. Meleddu R, et al. J Enzyme Inhib Med Chem. 2017 Dec;32(1):264-270. doi: 10.1080/14756366.2016.1247061. J Enzyme Inhib Med Chem. 2017. PMID: 28097874 Free PMC article.

9

Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions.

Meleddu R, Corona A, Distinto S, Cottiglia F, Deplano S, Sequeira L, Secci D, Onali A, Sanna E, Esposito F, Cirone I, Ortuso F, Alcaro S, Tramontano E, Mátyus P, Maccioni E. Meleddu R, et al. Molecules. 2021 Jun 23;26(13):3821. doi: 10.3390/molecules26133821. Molecules. 2021. PMID: 34201561 Free PMC article.

10

Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.

Maccioni E, Alcaro S, Orallo F, Cardia MC, Distinto S, Costa G, Yanez M, Sanna ML, Vigo S, Meleddu R, Secci D. Maccioni E, et al. Among authors: meleddu r. Eur J Med Chem. 2010 Oct;45(10):4490-8. doi: 10.1016/j.ejmech.2010.07.009. Epub 2010 Jul 17. Eur J Med Chem. 2010. PMID: 20702005

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