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The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.
Mercher T, Raffel GD, Moore SA, Cornejo MG, Baudry-Bluteau D, Cagnard N, Jesneck JL, Pikman Y, Cullen D, Williams IR, Akashi K, Shigematsu H, Bourquin JP, Giovannini M, Vainchenker W, Levine RL, Lee BH, Bernard OA, Gilliland DG. Mercher T, et al. Among authors: cornejo mg. J Clin Invest. 2009 Apr;119(4):852-64. doi: 10.1172/JCI35901. Epub 2009 Mar 16. J Clin Invest. 2009. PMID: 19287095 Free PMC article.
A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia.
Gu TL, Mercher T, Tyner JW, Goss VL, Walters DK, Cornejo MG, Reeves C, Popova L, Lee K, Heinrich MC, Rush J, Daibata M, Miyoshi I, Gilliland DG, Druker BJ, Polakiewicz RD. Gu TL, et al. Among authors: cornejo mg. Blood. 2007 Jul 1;110(1):323-33. doi: 10.1182/blood-2006-10-052282. Epub 2007 Mar 14. Blood. 2007. PMID: 17360941 Free PMC article.
JAK3: a two-faced player in hematological disorders.
Cornejo MG, Boggon TJ, Mercher T. Cornejo MG, et al. Int J Biochem Cell Biol. 2009 Dec;41(12):2376-9. doi: 10.1016/j.biocel.2009.09.004. Epub 2009 Sep 9. Int J Biochem Cell Biol. 2009. PMID: 19747563 Free PMC article. Review.
Direct inhibition of the NOTCH transcription factor complex.
Moellering RE, Cornejo M, Davis TN, Del Bianco C, Aster JC, Blacklow SC, Kung AL, Gilliland DG, Verdine GL, Bradner JE. Moellering RE, et al. Nature. 2009 Nov 12;462(7270):182-8. doi: 10.1038/nature08543. Nature. 2009. PMID: 19907488 Free PMC article.
14 results