Laznik D - Search Results

1

Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase.

Lustig Y, Ruas JL, Estall JL, Lo JC, Devarakonda S, Laznik D, Choi JH, Ono H, Olsen JV, Spiegelman BM. Lustig Y, et al. Among authors: laznik d. Genes Dev. 2011 Jun 15;25(12):1232-44. doi: 10.1101/gad.2054711. Epub 2011 Jun 6. Genes Dev. 2011. PMID: 21646374 Free PMC article.

2

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha.

Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM. Arany Z, et al. Among authors: laznik d. Nature. 2008 Feb 21;451(7181):1008-12. doi: 10.1038/nature06613. Nature. 2008. PMID: 18288196

3

Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation.

Arany Z, Wagner BK, Ma Y, Chinsomboon J, Laznik D, Spiegelman BM. Arany Z, et al. Among authors: laznik d. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4721-6. doi: 10.1073/pnas.0800979105. Epub 2008 Mar 17. Proc Natl Acad Sci U S A. 2008. PMID: 18347329 Free PMC article.

4

Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression.

Estall JL, Kahn M, Cooper MP, Fisher FM, Wu MK, Laznik D, Qu L, Cohen DE, Shulman GI, Spiegelman BM. Estall JL, et al. Among authors: laznik d. Diabetes. 2009 Jul;58(7):1499-508. doi: 10.2337/db08-1571. Epub 2009 Apr 14. Diabetes. 2009. PMID: 19366863 Free PMC article.

5

PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis.

Estall JL, Ruas JL, Choi CS, Laznik D, Badman M, Maratos-Flier E, Shulman GI, Spiegelman BM. Estall JL, et al. Among authors: laznik d. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22510-5. doi: 10.1073/pnas.0912533106. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2009. PMID: 20018698 Free PMC article.

6

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.

Choi JH, Banks AS, Estall JL, Kajimura S, Boström P, Laznik D, Ruas JL, Chalmers MJ, Kamenecka TM, Blüher M, Griffin PR, Spiegelman BM. Choi JH, et al. Among authors: laznik d. Nature. 2010 Jul 22;466(7305):451-6. doi: 10.1038/nature09291. Nature. 2010. PMID: 20651683 Free PMC article.

7

Development of insulin resistance in mice lacking PGC-1α in adipose tissues.

Kleiner S, Mepani RJ, Laznik D, Ye L, Jurczak MJ, Jornayvaz FR, Estall JL, Chatterjee Bhowmick D, Shulman GI, Spiegelman BM. Kleiner S, et al. Among authors: laznik d. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9635-40. doi: 10.1073/pnas.1207287109. Epub 2012 May 29. Proc Natl Acad Sci U S A. 2012. PMID: 22645355 Free PMC article.

8

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation.

Choi JH, Banks AS, Kamenecka TM, Busby SA, Chalmers MJ, Kumar N, Kuruvilla DS, Shin Y, He Y, Bruning JB, Marciano DP, Cameron MD, Laznik D, Jurczak MJ, Schürer SC, Vidović D, Shulman GI, Spiegelman BM, Griffin PR. Choi JH, et al. Among authors: laznik d. Nature. 2011 Sep 4;477(7365):477-81. doi: 10.1038/nature10383. Nature. 2011. PMID: 21892191 Free PMC article.

9

TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.

Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, Puigserver P, Griffin PR, Clapham DE, Spiegelman BM. Ye L, et al. Among authors: laznik d. Cell. 2012 Sep 28;151(1):96-110. doi: 10.1016/j.cell.2012.08.034. Cell. 2012. PMID: 23021218 Free PMC article.

10

Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice.

Banks AS, Kim-Muller JY, Mastracci TL, Kofler NM, Qiang L, Haeusler RA, Jurczak MJ, Laznik D, Heinrich G, Samuel VT, Shulman GI, Papaioannou VE, Accili D. Banks AS, et al. Among authors: laznik d. Cell Metab. 2011 Nov 2;14(5):587-97. doi: 10.1016/j.cmet.2011.09.012. Cell Metab. 2011. PMID: 22055502 Free PMC article.

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