Brown D - Search Results

1

Developing therapeutic microRNAs for cancer.

Bader AG, Brown D, Stoudemire J, Lammers P. Bader AG, et al. Among authors: brown d. Gene Ther. 2011 Dec;18(12):1121-6. doi: 10.1038/gt.2011.79. Epub 2011 Jun 2. Gene Ther. 2011. PMID: 21633392 Free PMC article. Review.

2

Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34.

Wiggins JF, Ruffino L, Kelnar K, Omotola M, Patrawala L, Brown D, Bader AG. Wiggins JF, et al. Among authors: brown d. Cancer Res. 2010 Jul 15;70(14):5923-30. doi: 10.1158/0008-5472.CAN-10-0655. Epub 2010 Jun 22. Cancer Res. 2010. PMID: 20570894 Free PMC article.

3

The promise of microRNA replacement therapy.

Bader AG, Brown D, Winkler M. Bader AG, et al. Among authors: brown d. Cancer Res. 2010 Sep 15;70(18):7027-30. doi: 10.1158/0008-5472.CAN-10-2010. Epub 2010 Aug 31. Cancer Res. 2010. PMID: 20807816 Free PMC article. Review.

4

Applying small RNA molecules to the directed treatment of human diseases: realizing the potential.

Pappas TC, Bader AG, Andruss BF, Brown D, Ford LP. Pappas TC, et al. Among authors: brown d. Expert Opin Ther Targets. 2008 Jan;12(1):115-27. doi: 10.1517/14728222.12.1.115. Expert Opin Ther Targets. 2008. PMID: 18076375 Review.

5

Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes.

Takeshita F, Patrawala L, Osaki M, Takahashi RU, Yamamoto Y, Kosaka N, Kawamata M, Kelnar K, Bader AG, Brown D, Ochiya T. Takeshita F, et al. Among authors: brown d. Mol Ther. 2010 Jan;18(1):181-7. doi: 10.1038/mt.2009.207. Epub 2009 Sep 8. Mol Ther. 2010. PMID: 19738602 Free PMC article.

6

Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice.

Trang P, Wiggins JF, Daige CL, Cho C, Omotola M, Brown D, Weidhaas JB, Bader AG, Slack FJ. Trang P, et al. Among authors: brown d. Mol Ther. 2011 Jun;19(6):1116-22. doi: 10.1038/mt.2011.48. Epub 2011 Mar 22. Mol Ther. 2011. PMID: 21427705 Free PMC article.

7

The let-7 microRNA reduces tumor growth in mouse models of lung cancer.

Esquela-Kerscher A, Trang P, Wiggins JF, Patrawala L, Cheng A, Ford L, Weidhaas JB, Brown D, Bader AG, Slack FJ. Esquela-Kerscher A, et al. Among authors: brown d. Cell Cycle. 2008 Mar 15;7(6):759-64. doi: 10.4161/cc.7.6.5834. Epub 2008 Mar 3. Cell Cycle. 2008. PMID: 18344688

8

Regression of murine lung tumors by the let-7 microRNA.

Trang P, Medina PP, Wiggins JF, Ruffino L, Kelnar K, Omotola M, Homer R, Brown D, Bader AG, Weidhaas JB, Slack FJ. Trang P, et al. Among authors: brown d. Oncogene. 2010 Mar 18;29(11):1580-7. doi: 10.1038/onc.2009.445. Epub 2009 Dec 7. Oncogene. 2010. PMID: 19966857 Free PMC article.

9

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44.

Liu C, Kelnar K, Liu B, Chen X, Calhoun-Davis T, Li H, Patrawala L, Yan H, Jeter C, Honorio S, Wiggins JF, Bader AG, Fagin R, Brown D, Tang DG. Liu C, et al. Among authors: brown d. Nat Med. 2011 Feb;17(2):211-5. doi: 10.1038/nm.2284. Epub 2011 Jan 16. Nat Med. 2011. PMID: 21240262 Free PMC article.

10

Systemic delivery of a miR34a mimic as a potential therapeutic for liver cancer.

Daige CL, Wiggins JF, Priddy L, Nelligan-Davis T, Zhao J, Brown D. Daige CL, et al. Among authors: brown d. Mol Cancer Ther. 2014 Oct;13(10):2352-60. doi: 10.1158/1535-7163.MCT-14-0209. Epub 2014 Jul 22. Mol Cancer Ther. 2014. PMID: 25053820

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