O'Dowd A - Search Results

1

Volunteer challenge with enterotoxigenic Escherichia coli that express intestinal colonization factor fimbriae CS17 and CS19.

McKenzie R, Porter CK, Cantrell JA, Denearing B, O'Dowd A, Grahek SL, Sincock SA, Woods C, Sebeny P, Sack DA, Tribble DR, Bourgeois AL, Savarino SJ. McKenzie R, et al. J Infect Dis. 2011 Jul 1;204(1):60-4. doi: 10.1093/infdis/jir220. J Infect Dis. 2011. PMID: 21628659 Free PMC article.

2

Prophylactic Efficacy of Hyperimmune Bovine Colostral Antiadhesin Antibodies Against Enterotoxigenic Escherichia coli Diarrhea: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial.

Savarino SJ, McKenzie R, Tribble DR, Porter CK, O'Dowd A, Cantrell JA, Sincock SA, Poole ST, DeNearing B, Woods CM, Kim H, Grahek SL, Brinkley C, Crabb JH, Bourgeois AL. Savarino SJ, et al. J Infect Dis. 2017 Jul 1;216(1):7-13. doi: 10.1093/infdis/jix144. J Infect Dis. 2017. PMID: 28541500 Clinical Trial.

3

Hyperimmune Bovine Colostral Anti-CS17 Antibodies Protect Against Enterotoxigenic Escherichia coli Diarrhea in a Randomized, Doubled-Blind, Placebo-Controlled Human Infection Model.

Savarino SJ, McKenzie R, Tribble DR, Porter CK, O'Dowd A, Sincock SA, Poole ST, DeNearing B, Woods CM, Kim H, Grahek SL, Brinkley C, Crabb JH, Bourgeois AL. Savarino SJ, et al. J Infect Dis. 2019 Jul 2;220(3):505-513. doi: 10.1093/infdis/jiz135. J Infect Dis. 2019. PMID: 30897198 Clinical Trial.

4

Immunogenicity of a prototype enterotoxigenic Escherichia coli adhesin vaccine in mice and nonhuman primates.

Sincock SA, Hall ER, Woods CM, O'Dowd A, Poole ST, McVeigh AL, Nunez G, Espinoza N, Miller M, Savarino SJ. Sincock SA, et al. Vaccine. 2016 Jan 4;34(2):284-291. doi: 10.1016/j.vaccine.2015.11.017. Epub 2015 Nov 18. Vaccine. 2016. PMID: 26597148

5

Evaluation of transcutaneous immunization as a delivery route for an enterotoxigenic E. coli adhesin-based vaccine with CfaE, the colonization factor antigen 1 (CFA/I) tip adhesin.

Rollenhagen JE, Woods CM, O'Dowd A, Poole ST, Tian JH, Guebre-Xabier M, Ellingsworth L, Prouty MG, Glenn G, Savarino SJ. Rollenhagen JE, et al. Vaccine. 2019 Sep 30;37(42):6134-6138. doi: 10.1016/j.vaccine.2019.08.057. Epub 2019 Sep 3. Vaccine. 2019. PMID: 31492474 Free article.

6

Establishment and Validation of Pathogenic CS17⁺ and CS19⁺ Enterotoxigenic Escherichia coli Challenge Models in the New World Primate Aotus nancymaae.

Hall ER, O'Dowd A, Rollenhagen JE, Espinoza N, Nunez G, Savarino SJ. Hall ER, et al. Infect Immun. 2021 Feb 16;89(3):e00479-20. doi: 10.1128/IAI.00479-20. Print 2021 Feb 16. Infect Immun. 2021. PMID: 33288648 Free PMC article.

7

Biochemical and immunological characterization of an ETEC CFA/I adhesin cholera toxin B subunit chimera.

Jobling MG, Poole ST, Rasulova-Lewis F, O'Dowd A, McVeigh AL, Balakrishnan A, Sincock SA, Prouty MG, Holmes RK, Savarino SJ. Jobling MG, et al. PLoS One. 2020 Mar 16;15(3):e0230138. doi: 10.1371/journal.pone.0230138. eCollection 2020. PLoS One. 2020. PMID: 32176708 Free PMC article.

8

Evaluation of the Immunogenicity and Protective Efficacy of an Enterotoxigenic Escherichia coli CFA/I Adhesin-Heat-Labile Toxin Chimera.

O'Dowd A, Maciel M Jr, Poole ST, Jobling MG, Rollenhagen JE, Woods CM, Sincock SA, McVeigh AL, Gregory MJ, Maves RC, Prouty MG, Holmes RK, Savarino SJ. O'Dowd A, et al. Infect Immun. 2020 Oct 19;88(11):e00252-20. doi: 10.1128/IAI.00252-20. Print 2020 Oct 19. Infect Immun. 2020. PMID: 32839188 Free PMC article.

9

Establishment, Validation, and Application of a New World Primate Model of Enterotoxigenic Escherichia coli Disease for Vaccine Development.

Rollenhagen JE, Jones F, Hall E, Maves R, Nunez G, Espinoza N, O'Dowd A, Prouty MG, Savarino SJ. Rollenhagen JE, et al. Infect Immun. 2019 Jan 24;87(2):e00634-18. doi: 10.1128/IAI.00634-18. Print 2019 Feb. Infect Immun. 2019. PMID: 30510102 Free PMC article.

10

Development and Comparison of a Panel of Modified CS17 Fimbrial Tip Adhesin Proteins as Components for an Adhesin-Based Vaccine against Enterotoxigenic Escherichia coli.

Liu Y, Maciel M Jr, O'Dowd A, Poole ST, Rollenhagen JE, Etobayeva IV, Savarino SJ. Liu Y, et al. Microorganisms. 2021 Jul 31;9(8):1646. doi: 10.3390/microorganisms9081646. Microorganisms. 2021. PMID: 34442726 Free PMC article.

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