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A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function.
Sadayappan S, Gulick J, Osinska H, Barefield D, Cuello F, Avkiran M, Lasko VM, Lorenz JN, Maillet M, Martin JL, Brown JH, Bers DM, Molkentin JD, James J, Robbins J. Sadayappan S, et al. Among authors: molkentin jd. Circ Res. 2011 Jul 8;109(2):141-50. doi: 10.1161/CIRCRESAHA.111.242560. Epub 2011 May 19. Circ Res. 2011. PMID: 21597010 Free PMC article.
Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice.
Bueno OF, Wilkins BJ, Tymitz KM, Glascock BJ, Kimball TF, Lorenz JN, Molkentin JD. Bueno OF, et al. Among authors: molkentin jd. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4586-91. doi: 10.1073/pnas.072647999. Epub 2002 Mar 19. Proc Natl Acad Sci U S A. 2002. PMID: 11904392 Free PMC article.
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD. Braz JC, et al. Among authors: molkentin jd. Nat Med. 2004 Mar;10(3):248-54. doi: 10.1038/nm1000. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966518 Free article.
MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo.
Lips DJ, Bueno OF, Wilkins BJ, Purcell NH, Kaiser RA, Lorenz JN, Voisin L, Saba-El-Leil MK, Meloche S, Pouysségur J, Pagès G, De Windt LJ, Doevendans PA, Molkentin JD. Lips DJ, et al. Among authors: molkentin jd. Circulation. 2004 Apr 27;109(16):1938-41. doi: 10.1161/01.CIR.0000127126.73759.23. Epub 2004 Apr 19. Circulation. 2004. PMID: 15096454
450 results