Duque-Afonso J - Search Results

1

The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO.

Duque-Afonso J, Yalcin A, Berg T, Abdelkarim M, Heidenreich O, Lübbert M. Duque-Afonso J, et al. Oncogene. 2011 Jul 7;30(27):3062-72. doi: 10.1038/onc.2011.32. Epub 2011 May 16. Oncogene. 2011. PMID: 21577204

2

Early-life infection depletes preleukemic cells in a mouse model of hyperdiploid B-cell acute lymphoblastic leukemia.

Farrokhi A, Atre T, Salitra S, Aletaha M, Márquez AC, Gynn M, Fidanza M, Jo S, Rolf N, Simmons K, Duque-Afonso J, Cleary ML, Seif AE, Kollmann T, Gantt S, Reid GSD. Farrokhi A, et al. Among authors: duque afonso j. Blood. 2024 Aug 22;144(8):809-821. doi: 10.1182/blood.2024025038. Blood. 2024. PMID: 38875504 Free PMC article.

3

XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from molecular pathogenesis to targeted therapy in leukemia and solid tumors.

Hackanson B, Becker H, Berg T, Binder M, Dierks C, Duque-Afonso J, Lairmore MD, Schäfer HS, Schnitzler M, Zeiser R, Martens U, Mertelsmann R, Lübbert M. Hackanson B, et al. Cancer Res. 2008 Jul 15;68(14):5512-8. doi: 10.1158/0008-5472.CAN-07-6859. Cancer Res. 2008. PMID: 18632600 Free PMC article. No abstract available.

4

Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes.

Hauswald S, Duque-Afonso J, Wagner MM, Schertl FM, Lübbert M, Peschel C, Keller U, Licht T. Hauswald S, et al. Clin Cancer Res. 2009 Jun 1;15(11):3705-15. doi: 10.1158/1078-0432.CCR-08-2048. Epub 2009 May 19. Clin Cancer Res. 2009. PMID: 19458058

5

The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells.

Almstedt M, Blagitko-Dorfs N, Duque-Afonso J, Karbach J, Pfeifer D, Jäger E, Lübbert M. Almstedt M, et al. Leuk Res. 2010 Jul;34(7):899-905. doi: 10.1016/j.leukres.2010.02.004. Epub 2010 Apr 10. Leuk Res. 2010. PMID: 20381863

6

Regulation of the adaptor molecule LAT2, an in vivo target gene of AML1/ETO (RUNX1/RUNX1T1), during myeloid differentiation.

Duque-Afonso J, Solari L, Essig A, Berg T, Pahl HL, Lübbert M. Duque-Afonso J, et al. Br J Haematol. 2011 Jun;153(5):612-22. doi: 10.1111/j.1365-2141.2011.08586.x. Epub 2011 Apr 13. Br J Haematol. 2011. PMID: 21488857 Free article.

7

Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat.

Blagitko-Dorfs N, Jiang Y, Duque-Afonso J, Hiller J, Yalcin A, Greve G, Abdelkarim M, Hackanson B, Lübbert M. Blagitko-Dorfs N, et al. PLoS One. 2013 Oct 8;8(10):e75258. doi: 10.1371/journal.pone.0075258. eCollection 2013. PLoS One. 2013. PMID: 24116031 Free PMC article.

8

The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells.

Essig A, Duque-Afonso J, Schwemmers S, Pahl HL, Lübbert M. Essig A, et al. Leuk Res. 2014 Mar;38(3):340-5. doi: 10.1016/j.leukres.2013.12.014. Epub 2013 Dec 25. Leuk Res. 2014. PMID: 24456692 Free PMC article.

9

Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia.

Becker H, Greve G, Kataoka K, Mallm JP, Duque-Afonso J, Ma T, Niemöller C, Pantic M, Duyster J, Cleary ML, Schüler J, Rippe K, Ogawa S, Lübbert M. Becker H, et al. Blood Adv. 2019 Mar 12;3(5):761-765. doi: 10.1182/bloodadvances.2018023879. Blood Adv. 2019. PMID: 30833276 Free PMC article.

10

The epigenetics of breast cancer - Opportunities for diagnostics, risk stratification and therapy.

Schröder R, Illert AL, Erbes T, Flotho C, Lübbert M, Duque-Afonso J. Schröder R, et al. Epigenetics. 2022 Jun;17(6):612-624. doi: 10.1080/15592294.2021.1940644. Epub 2021 Jun 23. Epigenetics. 2022. PMID: 34159881 Free PMC article.

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