Switzer K - Search Results

1

Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies.

Singh H, Figliola MJ, Dawson MJ, Huls H, Olivares S, Switzer K, Mi T, Maiti S, Kebriaei P, Lee DA, Champlin RE, Cooper LJ. Singh H, et al. Among authors: switzer k. Cancer Res. 2011 May 15;71(10):3516-27. doi: 10.1158/0008-5472.CAN-10-3843. Epub 2011 May 10. Cancer Res. 2011. PMID: 21558388 Free PMC article.

2

Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies.

Deniger DC, Maiti SN, Mi T, Switzer KC, Ramachandran V, Hurton LV, Ang S, Olivares S, Rabinovich BA, Huls MH, Lee DA, Bast RC Jr, Champlin RE, Cooper LJ. Deniger DC, et al. Among authors: switzer kc. Clin Cancer Res. 2014 Nov 15;20(22):5708-19. doi: 10.1158/1078-0432.CCR-13-3451. Epub 2014 May 15. Clin Cancer Res. 2014. PMID: 24833662 Free PMC article.

3

Genetic Engineering of T Cells to Target HERV-K, an Ancient Retrovirus on Melanoma.

Krishnamurthy J, Rabinovich BA, Mi T, Switzer KC, Olivares S, Maiti SN, Plummer JB, Singh H, Kumaresan PR, Huls HM, Wang-Johanning F, Cooper LJ. Krishnamurthy J, et al. Among authors: switzer kc. Clin Cancer Res. 2015 Jul 15;21(14):3241-51. doi: 10.1158/1078-0432.CCR-14-3197. Epub 2015 Mar 31. Clin Cancer Res. 2015. PMID: 25829402 Free PMC article.

4

Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells.

Hurton LV, Singh H, Najjar AM, Switzer KC, Mi T, Maiti S, Olivares S, Rabinovich B, Huls H, Forget MA, Datar V, Kebriaei P, Lee DA, Champlin RE, Cooper LJ. Hurton LV, et al. Among authors: switzer kc. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7788-E7797. doi: 10.1073/pnas.1610544113. Epub 2016 Nov 14. Proc Natl Acad Sci U S A. 2016. PMID: 27849617 Free PMC article.

5

Bispecific T-cells expressing polyclonal repertoire of endogenous γδ T-cell receptors and introduced CD19-specific chimeric antigen receptor.

Deniger DC, Switzer K, Mi T, Maiti S, Hurton L, Singh H, Huls H, Olivares S, Lee DA, Champlin RE, Cooper LJ. Deniger DC, et al. Among authors: switzer k. Mol Ther. 2013 Mar;21(3):638-47. doi: 10.1038/mt.2012.267. Epub 2013 Jan 8. Mol Ther. 2013. PMID: 23295945 Free PMC article.

6

Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity.

Caruso HG, Hurton LV, Najjar A, Rushworth D, Ang S, Olivares S, Mi T, Switzer K, Singh H, Huls H, Lee DA, Heimberger AB, Champlin RE, Cooper LJ. Caruso HG, et al. Among authors: switzer k. Cancer Res. 2015 Sep 1;75(17):3505-18. doi: 10.1158/0008-5472.CAN-15-0139. Cancer Res. 2015. PMID: 26330164 Free PMC article.

7

Antitumor activity of CD56-chimeric antigen receptor T cells in neuroblastoma and SCLC models.

Crossland DL, Denning WL, Ang S, Olivares S, Mi T, Switzer K, Singh H, Huls H, Gold KS, Glisson BS, Cooper LJ, Heymach JV. Crossland DL, et al. Among authors: switzer k. Oncogene. 2018 Jul;37(27):3686-3697. doi: 10.1038/s41388-018-0187-2. Epub 2018 Apr 6. Oncogene. 2018. PMID: 29622795

8

Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application.

Torikai H, Mi T, Gragert L, Maiers M, Najjar A, Ang S, Maiti S, Dai J, Switzer KC, Huls H, Dulay GP, Reik A, Rebar EJ, Holmes MC, Gregory PD, Champlin RE, Shpall EJ, Cooper LJ. Torikai H, et al. Among authors: switzer kc. Sci Rep. 2016 Feb 23;6:21757. doi: 10.1038/srep21757. Sci Rep. 2016. PMID: 26902653 Free PMC article.

9

Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy.

Hackett PB, Largaespada DA, Switzer KC, Cooper LJ. Hackett PB, et al. Among authors: switzer kc. Transl Res. 2013 Apr;161(4):265-83. doi: 10.1016/j.trsl.2012.12.005. Epub 2013 Jan 10. Transl Res. 2013. PMID: 23313630 Free PMC article. Review.

10

Corrective effects of interleukin-12 on age-related deficiencies in IFN-gamma production and IL-12Rbeta2 expression in virus-specific CD8+ T cells.

Zhang Y, Acuna CL, Switzer KC, Song L, Sayers R, Mbawuike IN. Zhang Y, et al. Among authors: switzer kc. J Interferon Cytokine Res. 2000 Feb;20(2):235-45. doi: 10.1089/107999000312658. J Interferon Cytokine Res. 2000. PMID: 10714560

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