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Aberrant TGFβ/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer.
Yeh KT, Chen TH, Yang HW, Chou JL, Chen LY, Yeh CM, Chen YH, Lin RI, Su HY, Chen GC, Deatherage DE, Huang YW, Yan PS, Lin HJ, Nephew KP, Huang TH, Lai HC, Chan MW. Yeh KT, et al. Among authors: huang th, huang yw. Epigenetics. 2011 Jun;6(6):727-39. doi: 10.4161/epi.6.6.15856. Epub 2011 Jun 1. Epigenetics. 2011. PMID: 21540640 Free PMC article.
Identification of candidate epigenetic biomarkers for ovarian cancer detection.
Huang YW, Jansen RA, Fabbri E, Potter D, Liyanarachchi S, Chan MW, Liu JC, Crijns AP, Brown R, Nephew KP, van der Zee AG, Cohn DE, Yan PS, Huang TH, Lin HJ. Huang YW, et al. Among authors: huang th. Oncol Rep. 2009 Oct;22(4):853-61. Oncol Rep. 2009. PMID: 19724865 Free PMC article.
Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer.
Chou JL, Su HY, Chen LY, Liao YP, Hartman-Frey C, Lai YH, Yang HW, Deatherage DE, Kuo CT, Huang YW, Yan PS, Hsiao SH, Tai CK, Lin HJ, Davuluri RV, Chao TK, Nephew KP, Huang TH, Lai HC, Chan MW. Chou JL, et al. Among authors: huang th, huang yw. Lab Invest. 2010 Mar;90(3):414-25. doi: 10.1038/labinvest.2009.138. Epub 2010 Jan 11. Lab Invest. 2010. PMID: 20065949 Free PMC article.
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