Thompson JA - Search Results

1

Protein damage from electrophiles and oxidants in lungs of mice chronically exposed to the tumor promoter butylated hydroxytoluene.

Shearn CT, Fritz KS, Thompson JA. Shearn CT, et al. Among authors: thompson ja. Chem Biol Interact. 2011 Jul 15;192(3):278-86. doi: 10.1016/j.cbi.2011.04.005. Epub 2011 Apr 21. Chem Biol Interact. 2011. PMID: 21536018

2

Carbonyl reductase inactivation may contribute to mouse lung tumor promotion by electrophilic metabolites of butylated hydroxytoluene: protein alkylation in vivo and in vitro.

Shearn CT, Fritz KS, Meier BW, Kirichenko OV, Thompson JA. Shearn CT, et al. Among authors: thompson ja. Chem Res Toxicol. 2008 Aug;21(8):1631-41. doi: 10.1021/tx800162p. Epub 2008 Jul 3. Chem Res Toxicol. 2008. PMID: 18597497

3

Responses of tumorigenic and non-tumorigenic mouse lung epithelial cell lines to electrophilic metabolites of the tumor promoter butylated hydroxytoluene.

Sun Y, Dwyer-Nield LD, Malkinson AM, Zhang YL, Thompson JA. Sun Y, et al. Among authors: thompson ja. Chem Biol Interact. 2003 Mar 6;145(1):41-51. doi: 10.1016/s0009-2797(02)00161-8. Chem Biol Interact. 2003. PMID: 12606153

4

Selective induction of apoptosis in mouse and human lung epithelial cell lines by the tert-butyl hydroxylated metabolite of butylated hydroxytoluene: a proposed role in tumor promotion.

Dwyer-Nield LD, Thompson JA, Peljak G, Squier MK, Barker TD, Parkinson A, Cohen JJ, Dinsdale D, Malkinson AM. Dwyer-Nield LD, et al. Among authors: thompson ja. Toxicology. 1998 Sep 15;130(2-3):115-27. doi: 10.1016/s0300-483x(98)00102-4. Toxicology. 1998. PMID: 9865479

5

Mechanistic basis for inflammation and tumor promotion in lungs of 2,6-di-tert-butyl-4-methylphenol-treated mice: electrophilic metabolites alkylate and inactivate antioxidant enzymes.

Meier BW, Gomez JD, Kirichenko OV, Thompson JA. Meier BW, et al. Among authors: thompson ja. Chem Res Toxicol. 2007 Feb;20(2):199-207. doi: 10.1021/tx060214f. Chem Res Toxicol. 2007. PMID: 17305404 Free PMC article.

6

Metabolic activation of butylated hydroxytoluene by mouse bronchiolar Clara cells.

Bolton JL, Thompson JA, Allentoff AJ, Miley FB, Malkinson AM. Bolton JL, et al. Among authors: thompson ja. Toxicol Appl Pharmacol. 1993 Nov;123(1):43-9. doi: 10.1006/taap.1993.1219. Toxicol Appl Pharmacol. 1993. PMID: 8236260

7

Transcriptional activity of quinone methides derived from the tumor promoter butylated hydroxytoluene in HepG2 cells.

Desjardins JP, Beard SE, Mapoles JE, Gee P, Thompson JA. Desjardins JP, et al. Among authors: thompson ja. Cancer Lett. 1998 Sep 25;131(2):201-7. doi: 10.1016/s0304-3835(98)00153-0. Cancer Lett. 1998. PMID: 9851254

8

Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion.

Thompson JA, Carlson TJ, Sun Y, Dwyer-Nield LD, Malkinson AM. Thompson JA, et al. Toxicology. 2001 Mar 7;160(1-3):197-205. doi: 10.1016/s0300-483x(00)00449-2. Toxicology. 2001. PMID: 11246140

9

Relationship between the metabolism of butylated hydroxytoluene (BHT) and lung tumor promotion in mice.

Thompson JA, Bolton JL, Malkinson AM. Thompson JA, et al. Exp Lung Res. 1991 Mar-Apr;17(2):439-53. doi: 10.3109/01902149109064431. Exp Lung Res. 1991. PMID: 2050043 Free article.

10

Immunochemical and proteomic analysis of covalent adducts formed by quinone methide tumor promoters in mouse lung epithelial cell lines.

Meier BW, Gomez JD, Zhou A, Thompson JA. Meier BW, et al. Among authors: thompson ja. Chem Res Toxicol. 2005 Oct;18(10):1575-85. doi: 10.1021/tx050108y. Chem Res Toxicol. 2005. PMID: 16533022

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