Gerona-Navarro G - Search Results

1

A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes.

Borah JC, Mujtaba S, Karakikes I, Zeng L, Muller M, Patel J, Moshkina N, Morohashi K, Zhang W, Gerona-Navarro G, Hajjar RJ, Zhou MM. Borah JC, et al. Among authors: gerona navarro g. Chem Biol. 2011 Apr 22;18(4):531-41. doi: 10.1016/j.chembiol.2010.12.021. Chem Biol. 2011. PMID: 21513889 Free PMC article.

2

Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors.

Gerona-Navarro G, Yoel-Rodríguez, Mujtaba S, Frasca A, Patel J, Zeng L, Plotnikov AN, Osman R, Zhou MM. Gerona-Navarro G, et al. J Am Chem Soc. 2011 Feb 23;133(7):2040-3. doi: 10.1021/ja107761h. Epub 2011 Jan 27. J Am Chem Soc. 2011. PMID: 21271695 Free PMC article.

3

Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression.

Gacias M, Gerona-Navarro G, Plotnikov AN, Zhang G, Zeng L, Kaur J, Moy G, Rusinova E, Rodriguez Y, Matikainen B, Vincek A, Joshua J, Casaccia P, Zhou MM. Gacias M, et al. Among authors: gerona navarro g. Chem Biol. 2014 Jul 17;21(7):841-854. doi: 10.1016/j.chembiol.2014.05.009. Epub 2014 Jun 19. Chem Biol. 2014. PMID: 24954007 Free PMC article.

4

Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300.

Zeng L, Zhang Q, Gerona-Navarro G, Moshkina N, Zhou MM. Zeng L, et al. Structure. 2008 Apr;16(4):643-52. doi: 10.1016/j.str.2008.01.010. Structure. 2008. PMID: 18400184 Free PMC article.

5

Modulating Mineralocorticoid Receptor with Non-steroidal Antagonists. New Opportunities for the Development of Potent and Selective Ligands without Off-Target Side Effects.

Martín-Martínez M, Pérez-Gordillo FL, Álvarez de la Rosa D, Rodríguez Y, Gerona-Navarro G, González-Muñiz R, Zhou MM. Martín-Martínez M, et al. Among authors: gerona navarro g. J Med Chem. 2017 Apr 13;60(7):2629-2650. doi: 10.1021/acs.jmedchem.6b01065. Epub 2017 Jan 24. J Med Chem. 2017. PMID: 28051871

6

In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4.

Rodríguez Y, Gerona-Navarro G, Osman R, Zhou MM. Rodríguez Y, et al. Among authors: gerona navarro g. Proteins. 2020 Mar;88(3):414-430. doi: 10.1002/prot.25818. Epub 2019 Oct 21. Proteins. 2020. PMID: 31587361 Free PMC article.

7

Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes.

Di Micco R, Fontanals-Cirera B, Low V, Ntziachristos P, Yuen SK, Lovell CD, Dolgalev I, Yonekubo Y, Zhang G, Rusinova E, Gerona-Navarro G, Cañamero M, Ohlmeyer M, Aifantis I, Zhou MM, Tsirigos A, Hernando E. Di Micco R, et al. Among authors: gerona navarro g. Cell Rep. 2014 Oct 9;9(1):234-247. doi: 10.1016/j.celrep.2014.08.055. Epub 2014 Sep 26. Cell Rep. 2014. PMID: 25263550 Free PMC article.

8

Assembling ligands in situ using bioorthogonal boronate ester synthesis.

Shin SB, Almeida RD, Gerona-Navarro G, Bracken C, Jaffrey SR. Shin SB, et al. Chem Biol. 2010 Nov 24;17(11):1171-6. doi: 10.1016/j.chembiol.2010.09.008. Chem Biol. 2010. PMID: 21095566 Free PMC article.

9

Ligand discovery using small molecule microarrays.

He XG, Gerona-Navarro G, Jaffrey SR. He XG, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):1-7. doi: 10.1124/jpet.104.076943. Epub 2004 Nov 10. J Pharmacol Exp Ther. 2005. PMID: 15537823 Review.

10

From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.

Gerona-Navarro G, Pérez de Vega MJ, García-López MT, Andrei G, Snoeck R, De Clercq E, Balzarini J, González-Muñiz R. Gerona-Navarro G, et al. J Med Chem. 2005 Apr 7;48(7):2612-21. doi: 10.1021/jm0492812. J Med Chem. 2005. PMID: 15801851

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