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A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay.
Smith ED, Ariane Vinson N, Zhong D, Berrang BD, Catanzaro JL, Thomas JB, Navarro HA, Gilmour BP, Deschamps J, Carroll FI. Smith ED, et al. Among authors: gilmour bp. Bioorg Med Chem. 2008 Jan 15;16(2):822-9. doi: 10.1016/j.bmc.2007.10.023. Epub 2007 Oct 13. Bioorg Med Chem. 2008. PMID: 17976996 Free PMC article.
Preparation of a Series of 5-Methyl-3-(substituted)-[1,2,4]triazines.
Gichinga MG, Olson JP, Butala E, Gilmour BP, Navarro HH, Carroll FI. Gichinga MG, et al. Among authors: gilmour bp. Tetrahedron Lett. 2011 Jun 29;52(26):3345-3346. doi: 10.1016/j.tetlet.2011.04.075. Tetrahedron Lett. 2011. PMID: 21779134 Free PMC article.
34 results