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A broad-spectrum antiviral targeting entry of enveloped viruses.
Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. Wolf MC, et al. Among authors: lee b. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. doi: 10.1073/pnas.0909587107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133606 Free PMC article.
Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation.
Garner OB, Aguilar HC, Fulcher JA, Levroney EL, Harrison R, Wright L, Robinson LR, Aspericueta V, Panico M, Haslam SM, Morris HR, Dell A, Lee B, Baum LG. Garner OB, et al. Among authors: lee b. PLoS Pathog. 2010 Jul 15;6(7):e1000993. doi: 10.1371/journal.ppat.1000993. PLoS Pathog. 2010. PMID: 20657665 Free PMC article.
Positive reinforcement for viruses.
Vigant F, Jung M, Lee B. Vigant F, et al. Among authors: lee b. Chem Biol. 2010 Oct 29;17(10):1049-51. doi: 10.1016/j.chembiol.2010.10.002. Chem Biol. 2010. PMID: 21035726 Free PMC article.
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