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Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts.
Guo L, Chen Z, Amarnath V, Yancey PG, Van Lenten BJ, Savage JR, Fazio S, Linton MF, Davies SS. Guo L, et al. Among authors: amarnath v. Antioxid Redox Signal. 2015 Jun 20;22(18):1633-45. doi: 10.1089/ars.2014.6078. Epub 2015 Mar 18. Antioxid Redox Signal. 2015. PMID: 25751734 Free PMC article.
Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia.
May-Zhang LS, Yermalitsky V, Melchior JT, Morris J, Tallman KA, Borja MS, Pleasent T, Amarnath V, Song W, Yancey PG, Davidson WS, Linton MF, Davies SS. May-Zhang LS, et al. Among authors: amarnath v. J Biol Chem. 2019 Dec 13;294(50):19022-19033. doi: 10.1074/jbc.RA119.009424. Epub 2019 Oct 30. J Biol Chem. 2019. PMID: 31666337 Free PMC article.
Isoketals form cytotoxic phosphatidylethanolamine adducts in cells.
Sullivan CB, Matafonova E, Roberts LJ 2nd, Amarnath V, Davies SS. Sullivan CB, et al. Among authors: amarnath v. J Lipid Res. 2010 May;51(5):999-1009. doi: 10.1194/jlr.M001040. Epub 2009 Nov 25. J Lipid Res. 2010. PMID: 19965577 Free PMC article.
113 results