Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR.
Huh JR, et al. Among authors: littman dr.
Nature. 2011 Apr 28;472(7344):486-90. doi: 10.1038/nature09978. Epub 2011 Mar 27.
Nature. 2011.
PMID: 21441909
Free PMC article.