Liu JY - Search Results

1

Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase.

Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD. Hwang SH, et al. Among authors: liu jy. J Med Chem. 2011 Apr 28;54(8):3037-50. doi: 10.1021/jm2001376. Epub 2011 Apr 5. J Med Chem. 2011. PMID: 21434686 Free PMC article.

2

Orally bioavailable potent soluble epoxide hydrolase inhibitors.

Hwang SH, Tsai HJ, Liu JY, Morisseau C, Hammock BD. Hwang SH, et al. Among authors: liu jy. J Med Chem. 2007 Aug 9;50(16):3825-40. doi: 10.1021/jm070270t. Epub 2007 Jul 6. J Med Chem. 2007. PMID: 17616115 Free PMC article.

3

Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation.

Liu JY, Tsai HJ, Hwang SH, Jones PD, Morisseau C, Hammock BD. Liu JY, et al. Br J Pharmacol. 2009 Jan;156(2):284-96. doi: 10.1111/j.1476-5381.2008.00009.x. Epub 2009 Jan 13. Br J Pharmacol. 2009. PMID: 19154430 Free PMC article.

4

Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo.

Liu JY, Park SH, Morisseau C, Hwang SH, Hammock BD, Weiss RH. Liu JY, et al. Mol Cancer Ther. 2009 Aug;8(8):2193-203. doi: 10.1158/1535-7163.MCT-09-0119. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671760 Free PMC article.

5

Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model.

Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD. Liu JY, et al. Biochem Pharmacol. 2010 Mar 15;79(6):880-7. doi: 10.1016/j.bcp.2009.10.025. Epub 2009 Nov 5. Biochem Pharmacol. 2010. PMID: 19896470 Free PMC article.

6

Soluble epoxide hydrolase inhibitors and heart failure.

Qiu H, Li N, Liu JY, Harris TR, Hammock BD, Chiamvimonvat N. Qiu H, et al. Among authors: liu jy. Cardiovasc Ther. 2011 Apr;29(2):99-111. doi: 10.1111/j.1755-5922.2010.00150.x. Cardiovasc Ther. 2011. PMID: 20433684 Free PMC article. Review.

7

1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain.

Rose TE, Morisseau C, Liu JY, Inceoglu B, Jones PD, Sanborn JR, Hammock BD. Rose TE, et al. Among authors: liu jy. J Med Chem. 2010 Oct 14;53(19):7067-75. doi: 10.1021/jm100691c. J Med Chem. 2010. PMID: 20812725 Free PMC article.

8

Incorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties.

Huang SX, Li HY, Liu JY, Morisseau C, Hammock BD, Long YQ. Huang SX, et al. Among authors: liu jy. J Med Chem. 2010 Dec 9;53(23):8376-86. doi: 10.1021/jm101087u. Epub 2010 Nov 11. J Med Chem. 2010. PMID: 21070033 Free PMC article.

9

Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model.

Liu JY, Qiu H, Morisseau C, Hwang SH, Tsai HJ, Ulu A, Chiamvimonvat N, Hammock BD. Liu JY, et al. Toxicol Appl Pharmacol. 2011 Sep 1;255(2):200-6. doi: 10.1016/j.taap.2011.06.017. Epub 2011 Jun 25. Toxicol Appl Pharmacol. 2011. PMID: 21741984 Free PMC article.

10

Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase.

Kim IH, Nishi K, Kasagami T, Morisseau C, Liu JY, Tsai HJ, Hammock BD. Kim IH, et al. Among authors: liu jy. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5889-92. doi: 10.1016/j.bmcl.2012.07.074. Epub 2012 Aug 2. Bioorg Med Chem Lett. 2012. PMID: 22901393 Free PMC article.

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