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VEGF inhibition increases expression of HIF-regulated angiogenic genes by the RPE limiting the response of wet AMD eyes to aflibercept.
Sharma D, Lau E, Qin Y, Jee K, Rodrigues M, Guo C, Dinabandhu A, McIntyre E, Salman S, Hwang Y, Moshiri A, Semenza GL, Montaner S, Sodhi A. Sharma D, et al. Among authors: guo c. Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2322759121. doi: 10.1073/pnas.2322759121. Epub 2024 Nov 5. Proc Natl Acad Sci U S A. 2024. PMID: 39499641
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