Wei W - Search Results

1

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W. Inuzuka H, et al. Among authors: wei w. Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732. Nature. 2011. PMID: 21368833 Free PMC article.

2

Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.

Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG Jr. Wei W, et al. Nature. 2004 Mar 11;428(6979):194-8. doi: 10.1038/nature02381. Nature. 2004. PMID: 15014503

3

Bioluminescent imaging of Cdk2 inhibition in vivo.

Zhang GJ, Safran M, Wei W, Sorensen E, Lassota P, Zhelev N, Neuberg DS, Shapiro G, Kaelin WG Jr. Zhang GJ, et al. Among authors: wei w. Nat Med. 2004 Jun;10(6):643-8. doi: 10.1038/nm1047. Epub 2004 May 2. Nat Med. 2004. PMID: 15122251

4

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.

Wei W, Jin J, Schlisio S, Harper JW, Kaelin WG Jr. Wei W, et al. Cancer Cell. 2005 Jul;8(1):25-33. doi: 10.1016/j.ccr.2005.06.005. Cancer Cell. 2005. PMID: 16023596 Free article.

5

Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.

Binné UK, Classon MK, Dick FA, Wei W, Rape M, Kaelin WG Jr, Näär AM, Dyson NJ. Binné UK, et al. Among authors: wei w. Nat Cell Biol. 2007 Feb;9(2):225-32. doi: 10.1038/ncb1532. Epub 2006 Dec 24. Nat Cell Biol. 2007. PMID: 17187060

6

Experimental approaches to investigate the proteasomal degradation pathways involved in regulation of apoptosis.

Tseng A, Inuzuka H, Gao D, Singh A, Wei W. Tseng A, et al. Among authors: wei w. Methods Enzymol. 2008;446:205-23. doi: 10.1016/S0076-6879(08)01612-1. Methods Enzymol. 2008. PMID: 18603124

7

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.

Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W. Gao D, et al. Among authors: wei w. Nat Cell Biol. 2009 Apr;11(4):397-408. doi: 10.1038/ncb1847. Epub 2009 Mar 8. Nat Cell Biol. 2009. PMID: 19270695 Free PMC article.

8

Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways.

Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, Kirschner M, Dyson N, Wei W. Gao D, et al. Among authors: wei w. Mol Biol Cell. 2009 Jul;20(14):3305-16. doi: 10.1091/mbc.e09-01-0092. Epub 2009 May 28. Mol Biol Cell. 2009. PMID: 19477924 Free PMC article.

9

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1.

Gao D, Inuzuka H, Tseng A, Wei W. Gao D, et al. Among authors: wei w. Cell Div. 2009 Jun 23;4:11. doi: 10.1186/1747-1028-4-11. Cell Div. 2009. PMID: 19549334 Free PMC article.

10

Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT.

Singh A, Ye M, Bucur O, Zhu S, Tanya Santos M, Rabinovitz I, Wei W, Gao D, Hahn WC, Khosravi-Far R. Singh A, et al. Among authors: wei w. Mol Biol Cell. 2010 Mar 15;21(6):1140-52. doi: 10.1091/mbc.e09-09-0795. Epub 2010 Jan 28. Mol Biol Cell. 2010. PMID: 20110348 Free PMC article.

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