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The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Leng S, Bernauer AM, Hong C, Do KC, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink RP, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello JF, Gilliland FD, Crowell RE, Belinsky SA. Leng S, et al. Among authors: do kc. Clin Cancer Res. 2011 Apr 1;17(7):2014-23. doi: 10.1158/1078-0432.CCR-10-3026. Epub 2011 Feb 25. Clin Cancer Res. 2011. PMID: 21355081 Free PMC article.
Defining a gene promoter methylation signature in sputum for lung cancer risk assessment.
Leng S, Do K, Yingling CM, Picchi MA, Wolf HJ, Kennedy TC, Feser WJ, Baron AE, Franklin WA, Brock MV, Herman JG, Baylin SB, Byers T, Stidley CA, Belinsky SA. Leng S, et al. Clin Cancer Res. 2012 Jun 15;18(12):3387-95. doi: 10.1158/1078-0432.CCR-11-3049. Epub 2012 Apr 17. Clin Cancer Res. 2012. PMID: 22510351 Free PMC article.
23 results