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Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice.
Kumar R, Hunt CR, Gupta A, Nannepaga S, Pandita RK, Shay JW, Bachoo R, Ludwig T, Burns DK, Pandita TK. Kumar R, et al. Among authors: pandita tk, pandita rk. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3636-41. doi: 10.1073/pnas.1016524108. Epub 2011 Feb 14. Proc Natl Acad Sci U S A. 2011. PMID: 21321203 Free PMC article.
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status.
Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, Gupta A, Rief N, Horikoshi N, Baskaran R, Lee JH, Löbrich M, Paull TT, Roti Roti JL, Pandita TK. Hunt CR, et al. Among authors: pandita tk, pandita rk. Cancer Res. 2007 Apr 1;67(7):3010-7. doi: 10.1158/0008-5472.CAN-06-4328. Cancer Res. 2007. PMID: 17409407
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis.
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. Gupta A, et al. Among authors: pandita s, pandita tk, pandita rk. Mol Cell Biol. 2008 Jan;28(1):397-409. doi: 10.1128/MCB.01045-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967868 Free PMC article.
Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest.
Singh M, Hunt CR, Pandita RK, Kumar R, Yang CR, Horikoshi N, Bachoo R, Serag S, Story MD, Shay JW, Powell SN, Gupta A, Jeffery J, Pandita S, Chen BP, Deckbar D, Löbrich M, Yang Q, Khanna KK, Worman HJ, Pandita TK. Singh M, et al. Among authors: pandita s, pandita tk, pandita rk. Mol Cell Biol. 2013 Mar;33(6):1210-22. doi: 10.1128/MCB.01676-12. Epub 2013 Jan 14. Mol Cell Biol. 2013. PMID: 23319047 Free PMC article.
MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.
Gupta A, Hunt CR, Hegde ML, Chakraborty S, Chakraborty S, Udayakumar D, Horikoshi N, Singh M, Ramnarain DB, Hittelman WN, Namjoshi S, Asaithamby A, Hazra TK, Ludwig T, Pandita RK, Tyler JK, Pandita TK. Gupta A, et al. Among authors: pandita tk, pandita rk. Cell Rep. 2014 Jul 10;8(1):177-89. doi: 10.1016/j.celrep.2014.05.044. Epub 2014 Jun 19. Cell Rep. 2014. PMID: 24953651 Free PMC article.
Role of HP1β during spermatogenesis and DNA replication.
Charaka V, Tiwari A, Pandita RK, Hunt CR, Pandita TK. Charaka V, et al. Among authors: pandita tk, pandita rk. Chromosoma. 2020 Dec;129(3-4):215-226. doi: 10.1007/s00412-020-00739-4. Epub 2020 Jul 10. Chromosoma. 2020. PMID: 32651609
115 results