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Page 1
5(Z)-benzylidene-1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5H-1-aza-6-oxa-chrysenes as non-steroidal glucocorticoid receptor modulators.
Ardecky RJ, Hudson AR, Phillips DP, Tyhonas JS, Deckhut C, Lau TL, Li Y, Martinborough EA, Roach SL, Higuchi RI, Lopez FJ, Marschke KB, Miner JN, Karanewsky DS, Negro-Vilar A, Zhi L. Ardecky RJ, et al. Among authors: miner jn. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4158-62. doi: 10.1016/j.bmcl.2007.05.062. Epub 2007 May 23. Bioorg Med Chem Lett. 2007. PMID: 17553679
Synthesis and characterization of nonsteroidal glucocorticoid receptor modulators for multiple myeloma.
Hudson AR, Roach SL, Higuchi RI, Phillips DP, Bissonnette RP, Lamph WW, Yen J, Li Y, Adams ME, Valdez LJ, Vassar A, Cuervo C, Kallel EA, Gharbaoui CJ, Mais DE, Miner JN, Marschke KB, Rungta D, Negro-Vilar A, Zhi L. Hudson AR, et al. Among authors: miner jn. J Med Chem. 2007 Sep 20;50(19):4699-709. doi: 10.1021/jm070370z. Epub 2007 Aug 17. J Med Chem. 2007. PMID: 17705362
A nonsteroidal glucocorticoid receptor antagonist.
Miner JN, Tyree C, Hu J, Berger E, Marschke K, Nakane M, Coghlan MJ, Clemm D, Lane B, Rosen J. Miner JN, et al. Mol Endocrinol. 2003 Jan;17(1):117-27. doi: 10.1210/me.2002-0010. Mol Endocrinol. 2003. PMID: 12511611
Nonsteroidal selective glucocorticoid modulators: the effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines.
Kym PR, Kort ME, Coghlan MJ, Moore JL, Tang R, Ratajczyk JD, Larson DP, Elmore SW, Pratt JK, Stashko MA, Falls HD, Lin CW, Nakane M, Miller L, Tyree CM, Miner JN, Jacobson PB, Wilcox DM, Nguyen P, Lane BC. Kym PR, et al. Among authors: miner jn. J Med Chem. 2003 Mar 13;46(6):1016-30. doi: 10.1021/jm020335m. J Med Chem. 2003. PMID: 12620078
75 results