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Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.
Volkmann K, Lucas JL, Vuga D, Wang X, Brumm D, Stiles C, Kriebel D, Der-Sarkissian A, Krishnan K, Schweitzer C, Liu Z, Malyankar UM, Chiovitti D, Canny M, Durocher D, Sicheri F, Patterson JB. Volkmann K, et al. Among authors: wang x. J Biol Chem. 2011 Apr 8;286(14):12743-55. doi: 10.1074/jbc.M110.199737. Epub 2011 Feb 8. J Biol Chem. 2011. PMID: 21303903 Free PMC article.
2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity.
Brown DG, Maier DL, Sylvester MA, Hoerter TN, Menhaji-Klotz E, Lasota CC, Hirata LT, Wilkins DE, Scott CW, Trivedi S, Chen T, McCarthy DJ, Maciag CM, Sutton EJ, Cumberledge J, Mathisen D, Roberts J, Gupta A, Liu F, Elmore CS, Alhambra C, Krumrine JR, Wang X, Ciaccio PJ, Wood MW, Campbell JB, Johansson MJ, Xia J, Wen X, Jiang J, Wang X, Peng Z, Hu T, Wang J. Brown DG, et al. Among authors: wang x, wang j. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3399-403. doi: 10.1016/j.bmcl.2011.03.117. Epub 2011 Apr 8. Bioorg Med Chem Lett. 2011. PMID: 21524576
Discovery of 4-morpholino-pyrimidin-6-one and 4-morpholino-pyrimidin-2-one-containing Phosphoinositide 3-kinase (PI3K) p110β isoform inhibitors through structure-based fragment optimisation.
Giordanetto F, Wållberg A, Cassel J, Ghosal S, Kossenjans M, Yuan ZQ, Wang X, Liang L. Giordanetto F, et al. Among authors: wang x. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6665-70. doi: 10.1016/j.bmcl.2012.08.101. Epub 2012 Sep 7. Bioorg Med Chem Lett. 2012. PMID: 23010274
Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.
Seifar F, Fox EJ, Shantaraman A, Liu Y, Dammer EB, Modeste E, Duong DM, Yin L, Trautwig AN, Guo Q, Xu K, Ping L, Reddy JS, Allen M, Quicksall Z, Heath L, Scanlan J, Wang E, Wang M, Linden AV, Poehlman W, Chen X, Baheti S, Ho C, Nguyen T, Yepez G, Mitchell AO, Oatman SR, Wang X, Carrasquillo MM, Runnels A, Beach T, Serrano GE, Dickson DW, Lee EB, Golde TE, Prokop S, Barnes LL, Zhang B, Haroutunian V, Gearing M, Lah JJ, De Jager P, Bennett DA, Greenwood A, Ertekin-Taner N, Levey AI, Wingo A, Wingo T, Seyfried NT. Seifar F, et al. Among authors: wang x. Alzheimers Dement. 2024 Nov 13. doi: 10.1002/alz.14360. Online ahead of print. Alzheimers Dement. 2024. PMID: 39535480
205,810 results
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