Moll UM - Search Results

1

Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes.

Beyer U, Moll-Rocek J, Moll UM, Dobbelstein M. Beyer U, et al. Among authors: moll um, moll rocek j. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3624-9. doi: 10.1073/pnas.1016201108. Epub 2011 Feb 7. Proc Natl Acad Sci U S A. 2011. PMID: 21300884 Free PMC article.

2

TAp73 is essential for germ cell adhesion and maturation in testis.

Holembowski L, Kramer D, Riedel D, Sordella R, Nemajerova A, Dobbelstein M, Moll UM. Holembowski L, et al. Among authors: moll um. J Cell Biol. 2014 Mar 31;204(7):1173-90. doi: 10.1083/jcb.201306066. Epub 2014 Mar 24. J Cell Biol. 2014. PMID: 24662569 Free PMC article.

3

The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteins.

Wolff S, Talos F, Palacios G, Beyer U, Dobbelstein M, Moll UM. Wolff S, et al. Among authors: moll um. Cell Death Differ. 2009 Aug;16(8):1108-17. doi: 10.1038/cdd.2009.25. Epub 2009 Mar 20. Cell Death Differ. 2009. PMID: 19300453 Free PMC article.

4

While p73 is essential, p63 is completely dispensable for the development of the central nervous system.

Holembowski L, Schulz R, Talos F, Scheel A, Wolff S, Dobbelstein M, Moll U. Holembowski L, et al. Cell Cycle. 2011 Feb 15;10(4):680-9. doi: 10.4161/cc.10.4.14859. Epub 2011 Feb 15. Cell Cycle. 2011. PMID: 21293190 Free PMC article.

5

Targeting tumour-supportive cellular machineries in anticancer drug development.

Dobbelstein M, Moll U. Dobbelstein M, et al. Nat Rev Drug Discov. 2014 Mar;13(3):179-96. doi: 10.1038/nrd4201. Nat Rev Drug Discov. 2014. PMID: 24577400 Review.

6

p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest.

Braun CJ, Zhang X, Savelyeva I, Wolff S, Moll UM, Schepeler T, Ørntoft TF, Andersen CL, Dobbelstein M. Braun CJ, et al. Among authors: moll um. Cancer Res. 2008 Dec 15;68(24):10094-104. doi: 10.1158/0008-5472.CAN-08-1569. Cancer Res. 2008. PMID: 19074875 Free PMC article.

7

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.

Schulz R, Marchenko ND, Holembowski L, Fingerle-Rowson G, Pesic M, Zender L, Dobbelstein M, Moll UM. Schulz R, et al. Among authors: moll um. J Exp Med. 2012 Feb 13;209(2):275-89. doi: 10.1084/jem.20111117. Epub 2012 Jan 23. J Exp Med. 2012. PMID: 22271573 Free PMC article.

8

HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates.

Schulz R, Dobbelstein M, Moll UM. Schulz R, et al. Among authors: moll um. Oncoimmunology. 2012 Nov 1;1(8):1425-1426. doi: 10.4161/onci.21173. Oncoimmunology. 2012. PMID: 23243616 Free PMC article.

9

MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP.

Zhang X, Schulz R, Edmunds S, Krüger E, Markert E, Gaedcke J, Cormet-Boyaka E, Ghadimi M, Beissbarth T, Levine AJ, Moll UM, Dobbelstein M. Zhang X, et al. Among authors: moll um. Mol Cell. 2015 Jul 16;59(2):243-57. doi: 10.1016/j.molcel.2015.05.036. Epub 2015 Jul 2. Mol Cell. 2015. PMID: 26145175 Free article.

10

Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.

Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Roßmann L, Bastians H, Concin N, Moll UM, Dobbelstein M. Kramer D, et al. Among authors: moll um. Cell Death Differ. 2017 Feb;24(2):300-316. doi: 10.1038/cdd.2016.124. Epub 2016 Nov 11. Cell Death Differ. 2017. PMID: 27834954 Free PMC article.

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