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Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series.
Nigrovic PA, Mannion M, Prince FH, Zeft A, Rabinovich CE, van Rossum MA, Cortis E, Pardeo M, Miettunen PM, Janow G, Birmingham J, Eggebeen A, Janssen E, Shulman AI, Son MB, Hong S, Jones K, Ilowite NT, Cron RQ, Higgins GC. Nigrovic PA, et al. Among authors: janssen e. Arthritis Rheum. 2011 Feb;63(2):545-55. doi: 10.1002/art.30128. Arthritis Rheum. 2011. PMID: 21280009 Free article. Clinical Trial.
Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis.
Henderson LA, Volpi S, Frugoni F, Janssen E, Kim S, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Beth Son M, Mathieu R, Zurakowski D, Yu N, Lebedeva T, Fuhlbrigge RC, Walter JE, Nee Lee Y, Nigrovic PA, Notarangelo LD. Henderson LA, et al. Among authors: janssen e. Arthritis Rheumatol. 2016 Jul;68(7):1758-68. doi: 10.1002/art.39606. Arthritis Rheumatol. 2016. PMID: 26815131 Free PMC article.
Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis.
Henderson LA, Hoyt KJ, Lee PY, Rao DA, Jonsson AH, Nguyen JP, Rutherford K, Julé AM, Charbonnier LM, Case S, Chang MH, Cohen EM, Dedeoglu F, Fuhlbrigge RC, Halyabar O, Hazen MM, Janssen E, Kim S, Lo J, Lo MS, Meidan E, Son MBF, Sundel RP, Stoll ML, Nusbaum C, Lederer JA, Chatila TA, Nigrovic PA. Henderson LA, et al. Among authors: janssen e. JCI Insight. 2020 Mar 26;5(6):e132508. doi: 10.1172/jci.insight.132508. JCI Insight. 2020. PMID: 32213704 Free PMC article.
Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis.
Julé AM, Hoyt KJ, Wei K, Gutierrez-Arcelus M, Taylor ML, Ng J, Lederer JA, Case SM, Chang MH, Cohen EM, Dedeoglu F, Hazen MM, Hausmann JS, Halyabar O, Janssen E, Lo J, Lo MS, Meidan E, Roberts JE, Son MBF, Sundel RP, Lee PY, Chatila T, Nigrovic PA, Henderson LA. Julé AM, et al. Among authors: janssen e. JCI Insight. 2021 Sep 22;6(18):e149185. doi: 10.1172/jci.insight.149185. JCI Insight. 2021. PMID: 34403374 Free PMC article.
Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children.
Lee PY, Day-Lewis M, Henderson LA, Friedman KG, Lo J, Roberts JE, Lo MS, Platt CD, Chou J, Hoyt KJ, Baker AL, Banzon TM, Chang MH, Cohen E, de Ferranti SD, Dionne A, Habiballah S, Halyabar O, Hausmann JS, Hazen MM, Janssen E, Meidan E, Nelson RW, Nguyen AA, Sundel RP, Dedeoglu F, Nigrovic PA, Newburger JW, Son MBF. Lee PY, et al. Among authors: janssen e. J Clin Invest. 2020 Nov 2;130(11):5942-5950. doi: 10.1172/JCI141113. J Clin Invest. 2020. PMID: 32701511 Free PMC article.
Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor alpha, and interleukin-6 levels in rheumatoid arthritis. Longitudinal evaluation during methotrexate and azathioprine therapy.
Barrera P, Boerbooms AM, Janssen EM, Sauerwein RW, Gallati H, Mulder J, de Boo T, Demacker PN, van de Putte LB, van der Meer JW. Barrera P, et al. Among authors: janssen em. Arthritis Rheum. 1993 Aug;36(8):1070-9. doi: 10.1002/art.1780360807. Arthritis Rheum. 1993. PMID: 8393676 Clinical Trial.
An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome.
Taylor ML, Hoyt KJ, Han J, Benson L, Case S, Chandler MT, Chang MH, Platt C, Cohen EM, Day-Lewis M, Dedeoglu F, Gorman M, Hausmann JS, Janssen E, Lee PY, Lo J, Priebe GP, Lo MS, Meidan E, Nigrovic PA, Roberts JE, Son MBF, Sundel RP, Alfieri M, Yeun JC, Shobiye DM, Degar B, Chang JC, Halyabar O, Hazen MM, Henderson LA. Taylor ML, et al. Among authors: janssen e. J Rheumatol. 2022 Sep;49(9):1042-1051. doi: 10.3899/jrheum.211219. Epub 2022 Jul 15. J Rheumatol. 2022. PMID: 35840156 Free PMC article.
Genetic diagnosis of immune dysregulation can lead to targeted therapy for interstitial lung disease: A case series and single center approach.
Wobma H, Perkins R, Bartnikas L, Dedeoğlu F, Chou J, Vleugels RA, Lo MS, Janssen E, Henderson LA, Whangbo J, Vargas SO, Fishman M, Krone KA, Casey A. Wobma H, et al. Among authors: janssen e. Pediatr Pulmonol. 2022 Jul;57(7):1577-1587. doi: 10.1002/ppul.25924. Epub 2022 May 3. Pediatr Pulmonol. 2022. PMID: 35426264 Free PMC article.
Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA.
Charbonnier LM, Janssen E, Chou J, Ohsumi TK, Keles S, Hsu JT, Massaad MJ, Garcia-Lloret M, Hanna-Wakim R, Dbaibo G, Alangari AA, Alsultan A, Al-Zahrani D, Geha RS, Chatila TA. Charbonnier LM, et al. Among authors: janssen e. J Allergy Clin Immunol. 2015 Jan;135(1):217-27. doi: 10.1016/j.jaci.2014.10.019. Epub 2014 Nov 17. J Allergy Clin Immunol. 2015. PMID: 25468195 Free PMC article.
780 results