Wang P - Search Results

1

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y. Xu W, et al. Among authors: wang p, wang b. Cancer Cell. 2011 Jan 18;19(1):17-30. doi: 10.1016/j.ccr.2010.12.014. Cancer Cell. 2011. PMID: 21251613 Free PMC article.

2

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha.

Zhao S, Lin Y, Xu W, Jiang W, Zha Z, Wang P, Yu W, Li Z, Gong L, Peng Y, Ding J, Lei Q, Guan KL, Xiong Y. Zhao S, et al. Among authors: wang p. Science. 2009 Apr 10;324(5924):261-5. doi: 10.1126/science.1170944. Science. 2009. PMID: 19359588 Free PMC article.

3

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.

Wang Y, Xiao M, Chen X, Chen L, Xu Y, Lv L, Wang P, Yang H, Ma S, Lin H, Jiao B, Ren R, Ye D, Guan KL, Xiong Y. Wang Y, et al. Among authors: wang p. Mol Cell. 2015 Feb 19;57(4):662-673. doi: 10.1016/j.molcel.2014.12.023. Epub 2015 Jan 15. Mol Cell. 2015. PMID: 25601757 Free PMC article.

4

Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents.

Wang P, Wu J, Ma S, Zhang L, Yao J, Hoadley KA, Wilkerson MD, Perou CM, Guan KL, Ye D, Xiong Y. Wang P, et al. Cell Rep. 2015 Dec 22;13(11):2353-2361. doi: 10.1016/j.celrep.2015.11.029. Epub 2015 Dec 10. Cell Rep. 2015. PMID: 26686626 Free PMC article.

5

Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.

Xia YK, Zeng YR, Zhang ML, Liu P, Liu F, Zhang H, He CX, Sun YP, Zhang JY, Zhang C, Song L, Ding C, Tang YJ, Yang Z, Yang C, Wang P, Guan KL, Xiong Y, Ye D. Xia YK, et al. Among authors: wang p. Protein Cell. 2021 Jul;12(7):557-577. doi: 10.1007/s13238-020-00754-2. Epub 2020 Jul 18. Protein Cell. 2021. PMID: 32683582 Free PMC article.

6

Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity.

Chen X, Zhou W, Song RH, Liu S, Wang S, Chen Y, Gao C, He C, Xiao J, Zhang L, Wang T, Liu P, Duan K, Cheng Z, Zhang C, Zhang J, Sun Y, Jackson F, Lan F, Liu Y, Xu Y, Wong JJ, Wang P, Yang H, Xiong Y, Chen T, Li Y, Ye D. Chen X, et al. Among authors: wang p, wang t, wang s. Sci Adv. 2022 Jan 28;8(4):eabl5220. doi: 10.1126/sciadv.abl5220. Epub 2022 Jan 26. Sci Adv. 2022. PMID: 35080973 Free PMC article.

7

Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis.

Sun R, Zhang Z, Bao R, Guo X, Gu Y, Yang W, Wei J, Chen X, Tong L, Meng J, Zhong C, Zhang C, Zhang J, Sun Y, Ling C, Tong X, Yu FX, Yu H, Qu W, Zhao B, Guo W, Qian M, Saiyin H, Liu Y, Liu RH, Xie C, Liu W, Xiong Y, Guan KL, Shi Y, Wang P, Ye D. Sun R, et al. Among authors: wang p. J Hepatol. 2022 Aug;77(2):453-466. doi: 10.1016/j.jhep.2022.02.030. Epub 2022 Mar 12. J Hepatol. 2022. PMID: 35292350

8

The immunometabolite itaconate stimulates OXGR1 to promote mucociliary clearance during the pulmonary innate immune response.

Zeng YR, Song JB, Wang D, Huang ZX, Zhang C, Sun YP, Shu G, Xiong Y, Guan KL, Ye D, Wang P. Zeng YR, et al. Among authors: wang p, wang d. J Clin Invest. 2023 Mar 15;133(6):e160463. doi: 10.1172/JCI160463. J Clin Invest. 2023. PMID: 36919698 Free PMC article.

9

Itaconate in host inflammation and defense.

Ye D, Wang P, Chen LL, Guan KL, Xiong Y. Ye D, et al. Among authors: wang p. Trends Endocrinol Metab. 2024 Jul;35(7):586-606. doi: 10.1016/j.tem.2024.02.004. Epub 2024 Mar 5. Trends Endocrinol Metab. 2024. PMID: 38448252 Review.

10

Temsirolimus inhibits FSP1 enzyme activity to induce ferroptosis and restrain liver cancer progression.

Tian RL, Wang TX, Huang ZX, Yang Z, Guan KL, Xiong Y, Wang P, Ye D. Tian RL, et al. Among authors: wang tx, wang p. J Mol Cell Biol. 2024 Sep 23:mjae036. doi: 10.1093/jmcb/mjae036. Online ahead of print. J Mol Cell Biol. 2024. PMID: 39313331

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