Donato NJ - Search Results

1

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.

Sun H, Kapuria V, Peterson LF, Fang D, Bornmann WG, Bartholomeusz G, Talpaz M, Donato NJ. Sun H, et al. Among authors: donato nj. Blood. 2011 Mar 17;117(11):3151-62. doi: 10.1182/blood-2010-03-276477. Epub 2011 Jan 19. Blood. 2011. PMID: 21248063 Free article.

2

Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells.

Bartholomeusz GA, Talpaz M, Kapuria V, Kong LY, Wang S, Estrov Z, Priebe W, Wu J, Donato NJ. Bartholomeusz GA, et al. Among authors: donato nj. Blood. 2007 Apr 15;109(8):3470-8. doi: 10.1182/blood-2006-02-005579. Epub 2007 Jan 3. Blood. 2007. PMID: 17202319 Free PMC article.

3

Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells.

Wu J, Meng F, Lu H, Kong L, Bornmann W, Peng Z, Talpaz M, Donato NJ. Wu J, et al. Among authors: donato nj. Blood. 2008 Apr 1;111(7):3821-9. doi: 10.1182/blood-2007-08-109330. Epub 2008 Jan 30. Blood. 2008. PMID: 18235045 Free PMC article.

4

Targets and effectors of the cellular response to aurora kinase inhibitor MK-0457 (VX-680) in imatinib sensitive and resistant chronic myelogenous leukemia.

Donato NJ, Fang D, Sun H, Giannola D, Peterson LF, Talpaz M. Donato NJ, et al. Biochem Pharmacol. 2010 Mar 1;79(5):688-97. doi: 10.1016/j.bcp.2009.10.009. Epub 2009 Oct 27. Biochem Pharmacol. 2010. PMID: 19874801

5

Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis.

Kapuria V, Peterson LF, Fang D, Bornmann WG, Talpaz M, Donato NJ. Kapuria V, et al. Among authors: donato nj. Cancer Res. 2010 Nov 15;70(22):9265-76. doi: 10.1158/0008-5472.CAN-10-1530. Epub 2010 Nov 2. Cancer Res. 2010. PMID: 21045142

6

Chronic myeloid leukemia stem cells and developing therapies.

Donato NJ, Peterson LF. Donato NJ, et al. Leuk Lymphoma. 2011 Feb;52 Suppl 1:60-80. doi: 10.3109/10428194.2010.546921. Leuk Lymphoma. 2011. PMID: 21299460 Review.

7

A novel small molecule deubiquitinase inhibitor blocks Jak2 signaling through Jak2 ubiquitination.

Kapuria V, Levitzki A, Bornmann WG, Maxwell D, Priebe W, Sorenson RJ, Showalter HD, Talpaz M, Donato NJ. Kapuria V, et al. Among authors: donato nj. Cell Signal. 2011 Dec;23(12):2076-85. doi: 10.1016/j.cellsig.2011.08.002. Epub 2011 Aug 9. Cell Signal. 2011. PMID: 21855629

8

Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies.

Peterson LF, Sun H, Liu Y, Potu H, Kandarpa M, Ermann M, Courtney SM, Young M, Showalter HD, Sun D, Jakubowiak A, Malek SN, Talpaz M, Donato NJ. Peterson LF, et al. Among authors: donato nj. Blood. 2015 Jun 4;125(23):3588-97. doi: 10.1182/blood-2014-10-605584. Epub 2015 Mar 26. Blood. 2015. PMID: 25814533 Free article.

9

BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

Donato NJ, Wu JY, Stapley J, Gallick G, Lin H, Arlinghaus R, Talpaz M. Donato NJ, et al. Blood. 2003 Jan 15;101(2):690-8. doi: 10.1182/blood.V101.2.690. Blood. 2003. PMID: 12509383 Free article.

10

Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance.

Chandra J, Tracy J, Loegering D, Flatten K, Verstovsek S, Beran M, Gorre M, Estrov Z, Donato N, Talpaz M, Sawyers C, Bhalla K, Karp J, Sausville E, Kaufmann SH. Chandra J, et al. Blood. 2006 Mar 15;107(6):2501-6. doi: 10.1182/blood-2005-07-2966. Epub 2005 Nov 15. Blood. 2006. PMID: 16291594 Free PMC article.

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